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Eric Nguyen

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Articles 35
Citations 522
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Recent Articles
1.
Nguyen E, Poli M, Durrant M, Kang B, Katrekar D, Li D, et al.
Science . 2024 Nov; 386(6723):eado9336. PMID: 39541441
The genome is a sequence that encodes the DNA, RNA, and proteins that orchestrate an organism's function. We present Evo, a long-context genomic foundation model with a frontier architecture trained...
2.
Nguyen E, Liu H, Ruan D
Med Phys . 2024 Oct; 52(1):321-328. PMID: 39431952
Background: Large foundation models, such as the Segment Anything Model (SAM), have shown remarkable performance in image segmentation tasks. However, the optimal approach to achieve true utility of these models...
3.
Belmore L, Ahn T, Nguyen E, Lenz T
Prehosp Emerg Care . 2024 Jul; 29(1):93-95. PMID: 38975709
Non-ST segment elevation myocardial infarction (NSTEMI) is a relatively unknown complication of injecting sublingual Suboxone (buprenorphine/naloxone). Buprenorphine/naloxone should be taken as a sublingual tablet or a buccal film and not...
4.
Emani P, Liu J, Clarke D, Jensen M, Warrell J, Gupta C, et al.
Science . 2024 May; 384(6698):eadi5199. PMID: 38781369
Single-cell genomics is a powerful tool for studying heterogeneous tissues such as the brain. Yet little is understood about how genetic variants influence cell-level gene expression. Addressing this, we uniformly...
5.
Emani P, Liu J, Clarke D, Jensen M, Warrell J, Gupta C, et al.
bioRxiv . 2024 Apr; PMID: 38562822
Single-cell genomics is a powerful tool for studying heterogeneous tissues such as the brain. Yet, little is understood about how genetic variants influence cell-level gene expression. Addressing this, we uniformly...
6.
Burgess L, Nguyen E, Tseng C, Guckenberger M, Lo S, Zhang B, et al.
Clin Transl Radiat Oncol . 2024 Jan; 45:100716. PMID: 38226025
Radiotherapy is the dominant treatment modality for painful spine and non-spine bone metastases (NSBM). Historically, this was achieved with conventional low dose external beam radiotherapy, however, stereotactic body radiotherapy (SBRT)...
7.
Nguyen E, Poli M, Faizi M, Thomas A, Birch-Sykes C, Wornow M, et al.
ArXiv . 2023 Jul; PMID: 37426456
Genomic (DNA) sequences encode an enormous amount of information for gene regulation and protein synthesis. Similar to natural language models, researchers have proposed foundation models in genomics to learn generalizable...
8.
Park T, Hirday R, Ali A, Megersa R, Villasmil R, Nguyen E, et al.
STAR Protoc . 2023 May; 4(2):102292. PMID: 37149860
Here, we present a protocol for differentiating human-induced pluripotent stem cells into three distinct mesodermal cell types: vascular endothelial cells (ECs), pericytes, and fibroblasts. We describe steps for using monolayer...
9.
Shi L, Bennett N, Nguyen E, MacDonald C, Wang A, Liu W
Med Phys . 2023 Apr; 50(7):4459-4465. PMID: 37060293
Background: High precision radiotherapy with small irradiator size has potential in many treatment applications involving small shallow targets, with small animal radio-neuromodulation as an intriguing example. A focused kV technique...
10.
Hartpence J, Barber J, Nguyen E
VideoGIE . 2023 Jan; 8(1):20-22. PMID: 36644250
Video 1A large, impacted gallstone is treated unsuccessfully with electrohydraulic lithotripsy; however, fragmentation and removal is accomplished using endoscopic laser lithotripsy.