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Eric M Patrick

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Citations 56
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Recent Articles
1.
Patrick E, Yadav R, Senanayake K, Cotter K, Putnam A, Jankowsky E, et al.
Nat Commun . 2025 Jan; 16(1):1015. PMID: 39863580
DEAD-box RNA-dependent ATPases are ubiquitous in all domains of life where they bind and remodel RNA and RNA-protein complexes. DEAD-box ATPases with helicase activity unwind RNA duplexes by local opening...
2.
Patrick E, Yadav R, Senanayake K, Cotter K, Putnam A, Jankowsky E, et al.
bioRxiv . 2024 Mar; PMID: 38496418
DEAD-box RNA helicases are ubiquitous in all domains of life where they bind and remodel RNA and RNA-protein complexes. DEAD-box helicases unwind RNA duplexes by local opening of helical regions...
3.
Klump B, Perez G, Patrick E, Adams-Boone K, Cohen S, Han L, et al.
Cell Rep . 2023 Jun; 42(6):112577. PMID: 37267110
Localization of a variety of RNAs to non-membrane-bound cellular compartments such as nucleoli and Cajal bodies is critical for their stability and function. The molecular mechanisms that underly the recruitment...
4.
Patrick E, Slivka J, Payne B, Comstock M, Schmidt J
Nat Chem Biol . 2020 Feb; 16(7):801-809. PMID: 32066968
Telomere maintenance by telomerase is essential for continuous proliferation of human cells and is vital for the survival of stem cells and 90% of cancer cells. To compensate for telomeric...
5.
Patrick E, Srinivasan S, Jankowsky E, Comstock M
Nat Chem Biol . 2016 Nov; 13(1):99-104. PMID: 27870836
The conserved Saccharomyces cerevisiae Ski2-like RNA helicase Mtr4p plays essential roles in eukaryotic nuclear RNA processing. RNA helicase activity of Mtr4p is critical for biological functions of the enzyme, but...
6.
Aleman E, de Silva C, Patrick E, Musier-Forsyth K, Rueda D
J Phys Chem Lett . 2014 May; 5(5):777-781. PMID: 24803990
Fluorescent nucleotide analogues, such as 2-aminopurine (2AP) and pyrrolo-C (PyC), have been extensively used to study nucleic acid local conformational dynamics in bulk experiments. Here we present a proof-of-principle approach...