Eckhard Jankowsky
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Explore the profile of Eckhard Jankowsky including associated specialties, affiliations and a list of published articles.
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92
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5061
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Recent Articles
1.
Patrick E, Yadav R, Senanayake K, Cotter K, Putnam A, Jankowsky E, et al.
Nat Commun
. 2025 Jan;
16(1):1015.
PMID: 39863580
DEAD-box RNA-dependent ATPases are ubiquitous in all domains of life where they bind and remodel RNA and RNA-protein complexes. DEAD-box ATPases with helicase activity unwind RNA duplexes by local opening...
2.
Patrick E, Yadav R, Senanayake K, Cotter K, Putnam A, Jankowsky E, et al.
bioRxiv
. 2024 Mar;
PMID: 38496418
DEAD-box RNA helicases are ubiquitous in all domains of life where they bind and remodel RNA and RNA-protein complexes. DEAD-box helicases unwind RNA duplexes by local opening of helical regions...
3.
Huang H, Shah H, Hao J, Lin J, Prayson R, Xie L, et al.
Neuro Oncol
. 2024 Mar;
26(8):1388-1401.
PMID: 38456228
Background: Hypoxia is associated with poor prognosis in many cancers including glioblastoma (GBM). Glioma stem-like cells (GSCs) often reside in hypoxic regions and serve as reservoirs for disease progression. Long...
4.
Venus S, Tandjigora K, Jankowsky E
J Mol Biol
. 2023 Jul;
435(19):168217.
PMID: 37517790
The DEAD-box RNA helicase DDX3X promotes translation initiation and associates with stress granules. A range of diverse viruses produce proteins that target DDX3X, including hepatitis C, dengue, vaccinia, and influenza...
5.
Bohnsack K, Yi S, Venus S, Jankowsky E, Bohnsack M
Nat Rev Mol Cell Biol
. 2023 Jul;
24(10):749-769.
PMID: 37474727
RNA helicases are highly conserved proteins that use nucleoside triphosphates to bind or remodel RNA, RNA-protein complexes or both. RNA helicases are classified into the DEAD-box, DEAH/RHA, Ski2-like, Upf1-like and...
6.
Rao A, Lyu B, Jahan I, Lubertozzi A, Zhou G, Tedeschi F, et al.
Development
. 2023 Jun;
150(20).
PMID: 37306388
The eIF4E family of translation initiation factors bind 5' methylated caps and act as the limiting step for mRNA translation. The canonical eIF4E1A is required for cell viability, yet other...
7.
Moon J, Zhou G, Jankowsky E, von Lintig J
PNAS Nexus
. 2023 Jun;
2(6):pgad167.
PMID: 37275262
A major cause for childhood blindness worldwide is attributed to nutritional vitamin A deficiency. Surprisingly, the molecular basis of the ensuing retinal degeneration has not been well defined. Abundant expression...
8.
Abeywansha T, Huang W, Ye X, Nawrocki A, Lan X, Jankowsky E, et al.
Nat Commun
. 2023 Apr;
14(1):2232.
PMID: 37076488
Arginyl-tRNA-protein transferase 1 (ATE1) is a master regulator of protein homeostasis, stress response, cytoskeleton maintenance, and cell migration. The diverse functions of ATE1 arise from its unique enzymatic activity to...
9.
Ye X, Yang W, Yi S, Zhao Y, Varani G, Jankowsky E, et al.
Nat Commun
. 2023 Feb;
14(1):701.
PMID: 36759600
Specificity of RNA-binding proteins for target sequences varies considerably. Yet, it is not understood how certain few proteins achieve markedly higher sequence specificity than most others. Here we show that...
10.
Sloan A, Lee-Poturalski C, Hoffman H, Harris P, Elder T, Richardson B, et al.
Neurooncol Adv
. 2022 Dec;
4(1):vdac172.
PMID: 36452274
Background: The interaction between platelets and cancer cells has been underexplored in solid tumor models that do not metastasize, for example, glioblastoma (GBM) where metastasis is rare. Histologically, it is...