Eric L Garcia
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Explore the profile of Eric L Garcia including associated specialties, affiliations and a list of published articles.
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15
Citations
438
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Recent Articles
1.
Matera A, Steiner R, Mills C, McMichael B, Herring L, Garcia E
Front RNA Res
. 2024 Nov;
2.
PMID: 39492846
Introduction: Molecular chaperones and co-chaperones are highly conserved cellular components that perform a variety of duties related to the proper three-dimensional folding of the proteome. The web of factors that...
2.
Matera A, Steiner R, Mills C, Herring L, Garcia E
bioRxiv
. 2024 Jun;
PMID: 38903116
Molecular chaperones and co-chaperones are highly conserved cellular components that perform variety of duties related to the proper three-dimensional folding of the proteome. The web of factors that carries out...
3.
Garcia E, Steiner R, Raimer A, Herring L, Matera A, Spring A
BMC Biol
. 2024 Apr;
22(1):94.
PMID: 38664795
Background: Spinal muscular atrophy (SMA) is a devastating neuromuscular disease caused by hypomorphic loss of function in the survival motor neuron (SMN) protein. SMA presents across a broad spectrum of...
4.
Garcia E, Steiner R, Raimer A, Herring L, Matera A, Spring A
bioRxiv
. 2024 Jan;
PMID: 38168196
Background: Spinal Muscular Atrophy (SMA) is a devastating neuromuscular disease caused by hypomorphic loss of function in the Survival Motor Neuron (SMN) protein. SMA presents across broad spectrum of disease...
5.
Garcia E
G3 (Bethesda)
. 2022 Aug;
12(9).
PMID: 35920767
Genetic disruptions to the biogenesis of spliceosomal small-nuclear ribonucleoproteins in Drosophila cause wide-spread alternative splicing changes, including changes to the splicing of pre-mRNA for Ribosomal protein S21 (RpS21). Using a...
6.
Garcia E, Wen Y, Praveen K, Matera A
RNA
. 2016 Jun;
22(8):1215-27.
PMID: 27268418
Survival motor neuron (SMN) functions in the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs) that catalyze pre-mRNA splicing. Here, we used disruptions in Smn and two additional snRNP biogenesis genes,...
7.
Garcia E, Lu Z, Meers M, Praveen K, Matera A
RNA
. 2013 Sep;
19(11):1510-6.
PMID: 24006466
Reduced levels of survival motor neuron (SMN) protein lead to a neuromuscular disease called spinal muscular atrophy (SMA). Animal models of SMA recapitulate many aspects of the human disease, including...
8.
Johnson S, Garcia E, Summers M, Telesnitsky A
Virology
. 2012 May;
430(2):100-9.
PMID: 22633243
The current model for MLV genomic RNA (gRNA) packaging predicts that of the thousands of Gag proteins in a budding virion, only a small number (≤1%) may be necessary to...
9.
Heng X, Kharytonchyk S, Garcia E, Lu K, Divakaruni S, LaCotti C, et al.
J Mol Biol
. 2012 Feb;
417(3):224-39.
PMID: 22306406
Assembly of human immunodeficiency virus type 1 (HIV-1) particles is initiated in the cytoplasm by the formation of a ribonucleoprotein complex comprising the dimeric RNA genome and a small number...
10.
Lu K, Heng X, Garyu L, Monti S, Garcia E, Kharytonchyk S, et al.
Science
. 2011 Oct;
334(6053):242-5.
PMID: 21998393
The 5'-leader of the HIV-1 genome regulates multiple functions during viral replication via mechanisms that have yet to be established. We developed a nuclear magnetic resonance approach that enabled direct...