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Eric D Zhu

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Articles 8
Citations 157
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Recent Articles
1.
Liu E, Zalutskaya A, Chae B, Zhu E, Gori F, Demay M
Endocrinology . 2014 Jul; 155(10):3750-6. PMID: 25057796
Phosphate and parathyroid hormone related peptide (PTHrP) are required for normal growth plate maturation. Hypophosphatemia impairs hypertrophic chondrocyte apoptosis leading to rachitic expansion of the growth plate; however, the effect...
2.
Zhu E, Louis L, Brooks D, Bouxsein M, Demay M
Endocrinology . 2014 Jan; 155(4):1188-96. PMID: 24422540
Bisphosphonates are effective for preventing and treating skeletal disorders associated with hyperresorption. Their safety and efficacy has been studied in adults where the growth plate is fused and there is...
3.
Luderer H, Nazarian R, Zhu E, Demay M
Endocrinology . 2012 Nov; 154(1):16-24. PMID: 23132743
The vitamin D receptor (VDR) has both 1,25-dihydroxyvitamin D-dependent and -independent actions in the epidermis. Ligand-dependent actions of the VDR have been shown to promote keratinocyte differentiation and to regulate...
4.
Miedlich S, Zhu E, Sabbagh Y, Demay M
Endocrinology . 2010 Aug; 151(10):4607-12. PMID: 20685875
Rickets is a growth plate abnormality observed in growing animals and humans. Rachitic expansion of the hypertrophic chondrocyte layer of the growth plate, in the setting of hypophosphatemia, is due...
5.
Zhu S, Zhu E, Provot S, Gori F
J Bone Miner Res . 2010 Jun; 25(11):2504-14. PMID: 20533303
Wdr5, a bone morphogenetic protein 2 (BMP-2)-induced protein belonging to the family of the WD repeat proteins, is expressed in proliferating and hypertrophic chondrocytes of the growth plate and in...
6.
Miedlich S, Zalutskaya A, Zhu E, Demay M
J Biol Chem . 2010 Apr; 285(24):18270-5. PMID: 20404333
Growth plate abnormalities, associated with impaired hypertrophic chondrocyte apoptosis, are observed in humans and animals with abnormalities of vitamin D action and renal phosphate reabsorption. Low circulating phosphate levels impair...
7.
Gori F, Zhu E, Demay M
Dev Biol . 2009 Feb; 329(1):36-43. PMID: 19217897
Wdr5 is developmentally expressed in osteoblasts and is required for osteoblast differentiation. Mice overexpressing Wdr5 under the control of the mouse alpha(1)I collagen promoter (Col I-Wdr5) display accelerated osteoblast differentiation...
8.
Zhu E, Demay M, Gori F
J Biol Chem . 2008 Jan; 283(12):7361-7. PMID: 18201971
Wdr5 is developmentally expressed in osteoblasts and accelerates osteoblast differentiation in vitro and in vivo. To address whether Wdr5 is essential for osteoblast differentiation, plasmid-based small interfering RNAs were used...