Eric Allemand
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Explore the profile of Eric Allemand including associated specialties, affiliations and a list of published articles.
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20
Citations
634
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Recent Articles
1.
Ma Y, Schwager Karpukhina A, Dib C, Gautier C, Hermine O, Allemand E, et al.
Sci Adv
. 2024 May;
10(18):eadl1922.
PMID: 38691604
The most common form of facioscapulohumeral dystrophy (FSHD1) is caused by a partial loss of the D4Z4 macrosatellite repeat array in the subtelomeric region of chromosome 4. Patients with FSHD1...
2.
Bignaud A, Cockram C, Borde C, Groseille J, Allemand E, Thierry A, et al.
Nat Struct Mol Biol
. 2024 Jan;
31(3):489-497.
PMID: 38177686
Transcription generates local topological and mechanical constraints on the DNA fiber, leading to the generation of supercoiled chromosome domains in bacteria. However, the global impact of transcription on chromosome organization...
3.
Smith C, Goyal A, Weichenhan D, Allemand E, Mayakonda A, Toprak U, et al.
Haematologica
. 2023 Jan;
108(5):1259-1271.
PMID: 36632736
T-cell acute lymphocytic leukemia protein 1 (TAL1) is one of the most frequently deregulated oncogenes in T-cell acute lymphoblastic leukemia (T-ALL). Its deregulation can occur through diverse cis-alterations, including SIL-TAL1...
4.
Allemand E, Ango F
Methods Mol Biol
. 2022 Jul;
2537:81-95.
PMID: 35895260
In Metazoa, the diversity of transcripts produced by the RNA Polymerase II is generated essentially through post-transcriptional processing of the nascent transcripts. The regulation of exon inclusion by alternative splicing...
5.
Dos Reis R, Kornobis E, Pereira A, Tores F, Carrasco J, Gautier C, et al.
Nat Commun
. 2022 Jun;
13(1):3507.
PMID: 35717442
Gephyrin (GPHN) regulates the clustering of postsynaptic components at inhibitory synapses and is involved in pathophysiology of neuropsychiatric disorders. Here, we uncover an extensive diversity of GPHN transcripts that are...
6.
Pagliuso A, Tham T, Allemand E, Robertin S, Dupuy B, Bertrand Q, et al.
Cell Host Microbe
. 2019 Nov;
26(6):823-835.e11.
PMID: 31761719
RNA-binding proteins (RBPs) perform key cellular activities by controlling the function of bound RNAs. The widely held assumption that RBPs are strictly intracellular has been challenged by the discovery of...
7.
Allemand E, Myers M, Garcia-Bernardo J, Harel-Bellan A, Krainer A, Muchardt C
PLoS Genet
. 2016 Sep;
12(9):e1006318.
PMID: 27662573
Several studies propose an influence of chromatin on pre-mRNA splicing, but it is still unclear how widespread and how direct this phenomenon is. We find here that when assembled in...
8.
Mauger O, Klinck R, Chabot B, Muchardt C, Allemand E, Batsche E
Nucleic Acids Res
. 2015 Jan;
43(3):1869-82.
PMID: 25605796
Alternative splicing is the main source of proteome diversity. Here, we have investigated how alternative splicing affects the function of two human histone methyltransferases (HMTase): G9A and SUV39H2. We show...
9.
Allemand E, Hastings M
Methods Mol Biol
. 2014 Feb;
1126:205-16.
PMID: 24549667
Pre-mRNA splicing is a complex process that is carried out by a large ribonucleoprotein enzyme, termed the spliceosome, which comprises up to 200 proteins. Despite this complexity, the role of...
10.
Shema-Yaacoby E, Nikolov M, Haj-Yahya M, Siman P, Allemand E, Yamaguchi Y, et al.
Cell Rep
. 2013 Aug;
4(3):601-8.
PMID: 23933260
Chromatin posttranslational modifications (PTMs), including monoubiquitylation of histone H2B on lysine 120 (H2Bub1), play a major role in regulating genome functions. To elucidate the molecular mechanisms of H2Bub1 activity, a...