Eric A Wold
Overview
Explore the profile of Eric A Wold including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
21
Citations
555
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Chen J, Garcia E, Merritt C, Zamora J, Bolinger A, Pazdrak K, et al.
J Med Chem
. 2023 Jul;
66(14):9992-10009.
PMID: 37462530
The serotonin 5-HT receptor (5-HTR) and 5-HTR localize to the brain and share overlapping signal transduction facets that contribute to their roles in cognition, mood, learning, and memory. Achieving selective...
2.
Liu Z, Li Y, Chen H, Lai H, Wang P, Wu S, et al.
J Med Chem
. 2022 Jan;
65(3):2388-2408.
PMID: 34982556
Bromodomain-containing protein 4 (BRD4) is an emerging epigenetic drug target for intractable inflammatory disorders. The lack of highly selective inhibitors among BRD4 family members has stalled the collective understanding of...
3.
Liu Z, Wang P, Wold E, Song Q, Zhao C, Wang C, et al.
J Med Chem
. 2021 Apr;
64(8):4257-4288.
PMID: 33822624
Canonical WNT signaling is an important developmental pathway that has attracted increased attention for anticancer drug discovery. From the production and secretion of WNT ligands, their binding to membrane receptors,...
4.
Xu J, Berastegui-Cabrera J, Carretero-Ledesma M, Chen H, Xue Y, Wold E, et al.
Int J Mol Sci
. 2021 Feb;
22(4).
PMID: 33562748
Human adenoviruses (HAdVs) display a wide range of tissue tropism and can cause an array of symptoms from mild respiratory illnesses to disseminated and life-threatening infections in immunocompromised individuals. However,...
5.
Ye N, Qin W, Tian S, Xu Q, Wold E, Zhou J, et al.
J Med Chem
. 2020 Oct;
63(24):15187-15217.
PMID: 33111525
The sigma-1 (σ) receptor, an enigmatic protein originally classified as an opioid receptor subtype, is now understood to possess unique structural and functional features of its own and play critical...
6.
Wold E, Garcia E, Wild C, Miszkiel J, Soto C, Chen J, et al.
J Med Chem
. 2020 Jun;
63(14):7529-7544.
PMID: 32567857
Targeting the serotonin (5-HT) 5-HT receptor (5-HTR) allosteric site to potentiate endogenous 5-HT tone may provide novel therapeutics to alleviate the impact of costly, chronic diseases such as obesity and...
7.
Liu Z, Chen H, Wang P, Li Y, Wold E, Leonard P, et al.
J Med Chem
. 2020 Apr;
63(10):5242-5256.
PMID: 32255647
Bromodomain-containing protein 4 (BRD4) represents a promising drug target for anti-inflammatory therapeutics. Herein, we report the design, synthesis, and pharmacological evaluation of novel chromone derivatives via scaffold hopping to discover...
8.
Wold E, Wild C, Cunningham K, Zhou J
Curr Top Med Chem
. 2019 Jul;
19(16):1381-1398.
PMID: 31288724
Serotonin (5-HT) 5-HT2C receptor (5-HT2CR) is recognized as a critical mediator of diseaserelated pathways and behaviors based upon actions in the central nervous system (CNS). Since 5-HT2CR is a class...
9.
Liu G, Yin T, Kim H, Ding C, Yu Z, Wang H, et al.
Eur J Med Chem
. 2019 Jun;
178:589-605.
PMID: 31220676
In an effort to develop novel Bax activators for breast cancer treatment, a series of diverse analogues have been designed and synthesized based on lead compound SMBA1 through several strategies,...
10.
Liu G, Wold E, Zhou J
Curr Top Med Chem
. 2019 May;
19(11):892-897.
PMID: 31074366
Chemical reactions that can proceed in living systems while not interfering with native biochemical processes are collectively referred to as bioorthogonal chemistry. Selectivity, efficiency, and aqueous compatibility are three significant...