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Eray Enustun

Explore the profile of Eray Enustun including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 542
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Recent Articles
1.
Riley E, Lyda J, Reyes-Matte O, Sugie J, Kasu I, Enustun E, et al.
Genes Dev . 2025 Mar; PMID: 40086876
sporulation entails a dramatic transformation of the two cells required to assemble a dormant spore, with the larger mother cell engulfing the smaller forespore to produce the "cell within a...
2.
Gu Y, Li H, Deep A, Enustun E, Zhang D, Corbett K
Mol Cell . 2025 Jan; 85(3):523-536.e6. PMID: 39742666
Prokaryotes possess diverse anti-bacteriophage immune systems, including the single-protein Shedu nuclease. Here, we reveal the structural basis for activation of Bacillus cereus Shedu. Two cryoelectron microscopy structures of Shedu show...
3.
Riley E, Lyda J, Reyes-Matte O, Sugie J, Kasu I, Enustun E, et al.
bioRxiv . 2024 Dec; PMID: 39651166
sporulation entails a dramatic transformation of the two cells required to assemble a dormant spore, with the larger mother cell engulfing the smaller forespore to produce the cell-within-a-cell structure that...
4.
Deep A, Liang Q, Enustun E, Pogliano J, Corbett K
Nature . 2024 Aug; 634(8033):432-439. PMID: 39112702
Bacteria and their viruses (bacteriophages or phages) are engaged in an intense evolutionary arms race. While the mechanisms of many bacterial antiphage defence systems are known, how these systems avoid...
5.
Morgan C, Enustun E, Armbruster E, Birkholz E, Prichard A, Forman T, et al.
Proc Natl Acad Sci U S A . 2024 Apr; 121(19):e2321190121. PMID: 38687783
Targeting proteins to specific subcellular destinations is essential in prokaryotes, eukaryotes, and the viruses that infect them. Chimalliviridae phages encapsulate their genomes in a nucleus-like replication compartment composed of the...
6.
Morgan C, Enustun E, Armbruster E, Birkholz E, Prichard A, Forman T, et al.
bioRxiv . 2024 Apr; PMID: 38562762
Significance Statement: The phage nucleus is an enclosed replication compartment built by Chimalliviridae phages that, similar to the eukaryotic nucleus, separates transcription from translation and selectively imports certain proteins. This...
7.
Enustun E, Armbruster E, Lee J, Zhang S, Yee B, Malukhina K, et al.
Nucleic Acids Res . 2024 Mar; 52(8):4440-4455. PMID: 38554115
Large-genome bacteriophages (jumbo phages) of the proposed family Chimalliviridae assemble a nucleus-like compartment bounded by a protein shell that protects the replicating phage genome from host-encoded restriction enzymes and DNA-targeting...
8.
Deep A, Liang Q, Enustun E, Pogliano J, Corbett K
bioRxiv . 2024 Jan; PMID: 38260510
Bacteria and the viruses that infect them (bacteriophages or phages) are engaged in an evolutionary arms race that has resulted in the development of hundreds of bacterial defense systems and...
9.
Enustun E, Armbruster E, Lee J, Zhang S, Yee B, Gu Y, et al.
bioRxiv . 2023 Oct; PMID: 37790334
Large-genome bacteriophages (jumbo phages) of the family assemble a nucleus-like compartment bounded by a protein shell that protects the replicating phage genome from host-encoded restriction enzymes and CRISPR/Cas nucleases. While...
10.
Armbruster E, Rani P, Lee J, Klusch N, Hutchings J, Hoffman L, et al.
bioRxiv . 2023 Oct; PMID: 37781618
Many eukaryotic viruses require membrane-bound compartments for replication, but no such organelles are known to be formed by prokaryotic viruses. Bacteriophages of the family sequester their genomes within a phage-generated...