Erawan Borkham-Kamphorst
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Explore the profile of Erawan Borkham-Kamphorst including associated specialties, affiliations and a list of published articles.
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46
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1384
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Recent Articles
11.
Asimakopoulou A, Borkham-Kamphorst E, Van de Leur E, Weiskirchen R
Data Brief
. 2017 Jul;
13:644-649.
PMID: 28725667
The data presented in this brief report support the research article "" [1, doi: 10.1016/j.bbadis.2017.04.006]. We tested whether the absence of Lipocalin-2 (LCN2) could dysregulate the phosphatidylinositol 3-kinase/protein kinase B...
12.
Altered mitochondrial and peroxisomal integrity in lipocalin-2-deficient mice with hepatic steatosis
Asimakopoulou A, Fulop A, Borkham-Kamphorst E, Van de Leur E, Gassler N, Berger T, et al.
Biochim Biophys Acta Mol Basis Dis
. 2017 Apr;
1863(9):2093-2110.
PMID: 28396286
Lipocalin-2 (LCN2) is a secreted adipokine that transports small hydrophobic molecules such as fatty acids and steroids. LCN2 limits bacterial growth by sequestering iron-containing siderophores and in mammalian liver protects...
13.
Borkham-Kamphorst E, Steffen B, Van de Leur E, Tihaa L, Haas U, Woitok M, et al.
Biochim Biophys Acta
. 2016 Jul;
1863(11):2604-2612.
PMID: 27452908
The endoplasmic reticulum (ER) is primarily recognized as the site of synthesis and folding of secreted membrane-bound and certain organelle-targeted proteins. Optimum protein folding requires several factors, including ATP, Ca...
14.
Schon H, Bartneck M, Borkham-Kamphorst E, Nattermann J, Lammers T, Tacke F, et al.
Front Pharmacol
. 2016 Mar;
7:33.
PMID: 26941644
The activation and transdifferentiation of hepatic stellate cells (HSCs) into contractile, matrix-producing myofibroblasts (MFBs) are central events in hepatic fibrogenesis. These processes are driven by autocrine- and paracrine-acting soluble factors...
15.
Buhl E, Djudjaj S, Babickova J, Klinkhammer B, Folestad E, Borkham-Kamphorst E, et al.
Kidney Int
. 2016 Mar;
89(4):848-61.
PMID: 26924050
Platelet-derived growth factor (PDGF)-D, a specific PDGF receptor β (PDGFR-β) ligand, mediates mesangial proliferation in vitro and in vivo. However, its role in renal development, physiology, and fibrosis is relatively...
16.
Borkham-Kamphorst E, Weiskirchen R
Cytokine Growth Factor Rev
. 2015 Nov;
28:53-61.
PMID: 26547628
Platelet derived growth factor (PDGF) signaling plays an important role in activated hepatic stellate cells and portal fibroblast proliferation, chemotaxis, migration and cell survival. PDGF receptors and ligands are upregulated...
17.
Borkham-Kamphorst E, Steffen B, Van de Leur E, Haas U, Tihaa L, Friedman S, et al.
Cell Signal
. 2015 Oct;
28(1):34-42.
PMID: 26515130
CCN1/CYR61 is a matricellular protein of the CCN family, comprising six secreted proteins specifically associated with the extracellular matrix (ECM). CCN1 acts as an enhancer of the cutaneous wound healing...
18.
Asimakopoulou A, Borkham-Kamphorst E, Tacke F, Weiskirchen R
Hepatology
. 2015 Jun;
63(2):669-71.
PMID: 26054053
No abstract available.
19.
Borkham-Kamphorst E, Meurer S, Van de Leur E, Haas U, Tihaa L, Weiskirchen R
Cell Signal
. 2015 Mar;
27(7):1305-14.
PMID: 25819339
Unlabelled: Platelet-derived growth factor-D (PDGF-D) is one member of PDGF growth factors and known to signal by binding to and activating its cognate receptor type β (PDGFR-β). Beside PDGF-B, PDGF-D...
20.
Tag C, Sauer-Lehnen S, Weiskirchen S, Borkham-Kamphorst E, Tolba R, Tacke F, et al.
J Vis Exp
. 2015 Mar;
(96).
PMID: 25741630
In most vertebrates, the liver produces bile that is necessary to emulsify absorbed fats and enable the digestion of lipids in the small intestine as well as to excrete bilirubin...