Ephron S Rosenzweig
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Explore the profile of Ephron S Rosenzweig including associated specialties, affiliations and a list of published articles.
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29
Citations
1778
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Recent Articles
1.
Huie J, Torres-Espin A, Sacramento J, Keller A, Joiner W, North R, et al.
Exp Neurol
. 2024 Oct;
383:114995.
PMID: 39393672
The complex and heterogeneous nature of spinal cord injury has limited translational bench-to-bedside results. The wide variety of data, including injury parameters, biochemical, histological, and behavioral outcome measures represent a...
2.
Wai G, Zdunowski S, Zhong H, Nielson J, Ferguson A, Strand S, et al.
Front Rehabil Sci
. 2023 Jun;
4:1205456.
PMID: 37378049
Introduction: The paralysis that occurs after a spinal cord injury, particularly during the early stages of post-lesion recovery (∼6 weeks), appears to be attributable to the inability to activate motor...
3.
Sinopoulou E, Rosenzweig E, Conner J, Gibbs D, Weinholtz C, Weber J, et al.
Neuron
. 2022 Aug;
110(18):2970-2983.e4.
PMID: 35917818
We used viral intersectional tools to map the entire projectome of corticospinal neurons associated with fine distal forelimb control in Fischer 344 rats and rhesus macaques. In rats, we found...
4.
North R, Wurr R, Macon R, Mannion C, Hyde J, Torres-Espin A, et al.
Annu Int Conf IEEE Eng Med Biol Soc
. 2021 Dec;
2021:6110-6115.
PMID: 34892511
Research using nonhuman primate models for human disease frequently requires behavioral observational techniques to quantify functional outcomes. The ability to assess reaching and grasping patterns is of particular interest in...
5.
Biscola N, Christe K, Rosenzweig E, Tuszynski M, Havton L
Sci Rep
. 2020 Oct;
10(1):16170.
PMID: 32999325
The lower urinary tract (LUT) and micturition reflexes are sexually dimorphic across mammals. Sex as a biological variable is also of critical importance for the development and translation of new...
6.
Rosenzweig E, Salegio E, Liang J, Weber J, Weinholtz C, Brock J, et al.
Nat Neurosci
. 2019 Jun;
22(8):1269-1275.
PMID: 31235933
Inhibitory extracellular matrices form around mature neurons as perineuronal nets containing chondroitin sulfate proteoglycans that limit axonal sprouting after CNS injury. The enzyme chondroitinase (Chase) degrades inhibitory chondroitin sulfate proteoglycans...
7.
Kumamaru H, Lu P, Rosenzweig E, Kadoya K, Tuszynski M
Cell Rep
. 2019 Feb;
26(9):2329-2339.e4.
PMID: 30811984
Neural progenitor cell grafts form new relays across sites of spinal cord injury (SCI). Using a panel of neuronal markers, we demonstrate that spinal neural progenitor grafts to sites of...
8.
Kumamaru H, Lu P, Rosenzweig E, Tuszynski M
Stem Cell Reports
. 2018 Sep;
11(4):861-868.
PMID: 30197116
Axonal regeneration after spinal cord injury (SCI) can be enhanced by activation of the intrinsic neuronal growth state and, separately, by placement of growth-enabling neural progenitor cell (NPC) grafts into...
9.
Rosenzweig E, Brock J, Lu P, Kumamaru H, Salegio E, Kadoya K, et al.
Nat Med
. 2018 Feb;
24(4):484-490.
PMID: 29480894
We grafted human spinal cord-derived neural progenitor cells (NPCs) into sites of cervical spinal cord injury in rhesus monkeys (Macaca mulatta). Under three-drug immunosuppression, grafts survived at least 9 months...
10.
Salegio E, Bresnahan J, Sparrey C, Camisa W, Fischer J, Leasure J, et al.
J Neurotrauma
. 2016 Jan;
33(5):439-59.
PMID: 26788611
The development of a non-human primate (NHP) model of spinal cord injury (SCI) based on mechanical and computational modeling is described. We scaled up from a rodent model to a...