Enrico Carlon
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Explore the profile of Enrico Carlon including associated specialties, affiliations and a list of published articles.
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35
Citations
241
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Recent Articles
1.
Remini L, Segers M, Parmeggiani A, Carlon E
J Chem Phys
. 2025 Feb;
162(5).
PMID: 39902691
We analyze multiplexed fluorescence in situ hybridization (m-FISH) data for human and mouse cell lines. The m-FISH technique uses fluorescently-labeled single-stranded probes which hybridize to specific chromosomal regions, thereby allowing...
2.
Laeremans W, Segers M, Voorspoels A, Carlon E, Hooyberghs J
J Chem Phys
. 2024 Apr;
160(14).
PMID: 38591677
Coarse-grained models have emerged as valuable tools to simulate long DNA molecules while maintaining computational efficiency. These models aim at preserving interactions among coarse-grained variables in a manner that mirrors...
3.
Remini L, Segers M, Palmeri J, Walter J, Parmeggiani A, Carlon E
Phys Rev E
. 2024 Mar;
109(2-1):024408.
PMID: 38491617
Recent advances in experimental fluorescence microscopy allow high accuracy determination (resolution of 50 nm) of the three-dimensional physical location of multiple (up to ∼10^{2}) tagged regions of the chromosome. We...
4.
Segers M, Voorspoels A, Sakaue T, Carlon E
Phys Rev Lett
. 2023 Dec;
131(23):238402.
PMID: 38134780
Proteins often regulate their activities via allostery-or action at a distance-in which the binding of a ligand at one binding site influences the affinity for another ligand at a distal...
5.
Vanderlinden W, Skoruppa E, Kolbeck P, Carlon E, Lipfert J
PNAS Nexus
. 2023 Jan;
1(5):pgac268.
PMID: 36712371
DNA supercoiling is a key regulatory mechanism that orchestrates DNA readout, recombination, and genome maintenance. DNA-binding proteins often mediate these processes by bringing two distant DNA sites together, thereby inducing...
6.
Voorspoels A, Vreede J, Carlon E
J Chem Theory Comput
. 2023 Jan;
19(3):902-909.
PMID: 36695645
All-atom simulations have become increasingly popular to study conformational and dynamical properties of nucleic acids as they are accurate and provide high spatial and time resolutions. This high resolution, however,...
7.
Skoruppa E, Carlon E
Phys Rev E
. 2022 Sep;
106(2-1):024412.
PMID: 36109921
Plectonemes are intertwined helically looped domains which form when a DNA molecule is supercoiled, i.e., over- or underwound. They are ubiquitous in cellular DNA, and their physical properties have attracted...
8.
Huang G, Voorspoels A, Abraham Versloot R, van der Heide N, Carlon E, Willems K, et al.
Angew Chem Int Ed Engl
. 2022 Jun;
61(34):e202206227.
PMID: 35759385
The real-time identification of protein biomarkers is crucial for the development of point-of-care and portable devices. Here, we use a PlyAB biological nanopore to detect haemoglobin (Hb) variants. Adult haemoglobin...
9.
Segers M, Voorspoels A, Sakaue T, Carlon E
J Chem Phys
. 2022 Jun;
156(23):234105.
PMID: 35732531
Mechanical properties of nucleic acids play an important role in many biological processes that often involve physical deformations of these molecules. At sufficiently long length scales (say, above ∼20-30 base...
10.
Nomidis S, Carlon E, Gruber S, Marko J
Nucleic Acids Res
. 2022 Apr;
50(9):4974-4987.
PMID: 35474142
Structural Maintenance of Chromosomes (SMC) complexes play essential roles in genome organization across all domains of life. To determine how the activities of these large (≈50 nm) complexes are controlled...