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Ennio De Gregorio

Explore the profile of Ennio De Gregorio including associated specialties, affiliations and a list of published articles. Areas
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Articles 61
Citations 4055
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Recent Articles
1.
Rappuoli R, De Gregorio E, Del Giudice G, Phogat S, Pecetta S, Pizza M, et al.
Proc Natl Acad Sci U S A . 2021 Jan; 118(3). PMID: 33431690
The COVID-19 pandemic is a shocking reminder of how our world would look in the absence of vaccination. Fortunately, new technologies, the pace of understanding new and existing pathogens, and...
2.
Rappuoli R, De Gregorio E, Costantino P
Proc Natl Acad Sci U S A . 2018 Dec; 116(1):14-16. PMID: 30578318
No abstract available.
3.
Baker S, Payne D, Rappuoli R, De Gregorio E
Proc Natl Acad Sci U S A . 2018 Dec; 115(51):12887-12895. PMID: 30559181
Bacterial infections have been traditionally controlled by antibiotics and vaccines, and these approaches have greatly improved health and longevity. However, multiple stakeholders are declaring that the lack of new interventions...
4.
Francica J, Zak D, Linde C, Siena E, Johnson C, Juraska M, et al.
Blood Adv . 2018 Jan; 1(25):2329-2342. PMID: 29296883
Adjuvants have a critical role for improving vaccine efficacy against many pathogens, including HIV. Here, using transcriptional RNA profiling and systems serology, we assessed how distinct innate pathways altered HIV-specific...
5.
Cioncada R, Maddaluno M, Vo H, Woodruff M, Tavarini S, Sammicheli C, et al.
PLoS One . 2017 Nov; 12(10):e0185843. PMID: 29088224
MF59 is an oil-in-water emulsion adjuvant approved for human influenza vaccination in European Union. The mode of action of MF59 is not fully elucidated yet, but results from several years...
6.
Liang F, Lindgren G, Sandgren K, Thompson E, Francica J, Seubert A, et al.
Sci Transl Med . 2017 Jun; 9(393). PMID: 28592561
The innate immune mechanisms by which adjuvants enhance the potency and protection of vaccine-induced adaptive immunity are largely unknown. We introduce a model to delineate the steps of how adjuvant-driven...
7.
Kaslow D, Kalil J, Bloom D, Breghi G, Colucci A, De Gregorio E, et al.
Vaccine . 2016 Dec; 35 Suppl 1:A10-A15. PMID: 28017438
On 17 and 18 July 2015, a meeting in Siena jointly sponsored by ADITEC and GlaxoSmithKline (GSK) was held to review the goals of the Global Health 2035 Grand Convergence,...
8.
Corrado A, Donato P, Maccari S, Cecchi R, Spadafina T, Arcidiacono L, et al.
Sci Rep . 2016 Dec; 6:38043. PMID: 27901071
Staphylococcus aureus is the major cause of human septic arthritis and osteomyelitis, which deserve special attention due to their rapid evolution and resistance to treatment. The progression of the disease...
9.
Magini D, Giovani C, Mangiavacchi S, Maccari S, Cecchi R, Ulmer J, et al.
PLoS One . 2016 Aug; 11(8):e0161193. PMID: 27525409
Current hemagglutinin (HA)-based seasonal influenza vaccines induce vaccine strain-specific neutralizing antibodies that usually fail to provide protection against mismatched circulating viruses. Inclusion in the vaccine of highly conserved internal proteins...
10.
Rappuoli R, De Gregorio E
Curr Opin Immunol . 2016 Aug; 41:v-vii. PMID: 27499109
No abstract available.