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Eng Piew Louis Kok

Explore the profile of Eng Piew Louis Kok including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Wang Y, Liu K, Liu M, Ooi K, Nguyen T, Chee J, et al.
Nat Biotechnol . 2024 Oct; PMID: 39385008
Inactive Cas13 orthologs have been fused to a mutant human ADAR2 deaminase domain at the C terminus to enable programmable adenosine-to-inosine (A-to-I) RNA editing in selected transcripts. Although promising, existing...
2.
Nguyen T, Heng J, Kaewsapsak P, Kok E, Stanojevic D, Liu H, et al.
Nat Methods . 2022 Jun; 19(7):833-844. PMID: 35697834
Inosine is a prevalent RNA modification in animals and is formed when an adenosine is deaminated by the ADAR family of enzymes. Traditionally, inosines are identified indirectly as variants from...
3.
Srinivasan H, Kok E, Tan M
Methods Mol Biol . 2020 Jul; 2181:163-176. PMID: 32729080
Adenosine-to-inosine (A-to-I) RNA editing is a fundamental posttranscriptional mechanism that greatly diversifies the transcriptome in many living organisms, including mammals. Multiple studies have demonstrated the importance of this process not...