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Emoke Olah

Explore the profile of Emoke Olah including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 45
Followers 0
Related Specialties
Neurology
Emergency Medicine
Physiology
Top 10 Co-Authors
Andras Garami
Zoltan Rumbus
Eszter Pakai
Peter Hegyi
Andrej A Romanovsky
Laszlo Poto
Valeria Tekus
Patrik Keringer
Nikolett Szentes
Margit Solymar
Published In
J Neurotrauma
Front Immunol
Biomedicines
Pharmaceuticals (Basel)
Front Physiol
Affiliations
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Recent Articles
1.
The hyperthermic effect of central cholecystokinin is mediated by the cyclooxygenase-2 pathway
Keringer P, Furedi N, Gaszner B, Miko A, Pakai E, Fekete K, et al.
Am J Physiol Endocrinol Metab . 2021 Nov; 322(1):E10-E23. PMID: 34779255
Cholecystokinin (CCK) increases core body temperature via CCK receptors when administered intracerebroventricularly (icv). The mechanisms of CCK-induced hyperthermia are unknown, and it is also unknown whether CCK contributes to the...
2.
The Hypothermic Effect of Hydrogen Sulfide Is Mediated by the Transient Receptor Potential Ankyrin-1 Channel in Mice
Olah E, Rumbus Z, Kormos V, Tekus V, Pakai E, Wilson H, et al.
Pharmaceuticals (Basel) . 2021 Oct; 14(10). PMID: 34681216
Hydrogen sulfide (HS) has been shown in previous studies to cause hypothermia and hypometabolism in mice, and its thermoregulatory effects were subsequently investigated. However, the molecular target through which HS...
3.
Proof-of-Concept for the Analgesic Effect and Thermoregulatory Safety of Orally Administered Multi-Target Compound SZV 1287 in Mice: A Novel Drug Candidate for Neuropathic Pain
Horvath A, Szentes N, Tekus V, Payrits M, Szoke E, Olah E, et al.
Biomedicines . 2021 Jul; 9(7). PMID: 34209525
SZV 1287 (3-(4,5-diphenyl-1,3-oxazol-2-yl)propanal oxime) is a novel multi-target candidate under preclinical development for neuropathic pain. It inhibits amine oxidase copper containing 3, transient receptor potential ankyrin 1 and vanilloid 1...
4.
POLAR Study Revisited: Therapeutic Hypothermia in Severe Brain Trauma Should Not Be Abandoned
Olah E, Poto L, Rumbus Z, Pakai E, Romanovsky A, Hegyi P, et al.
J Neurotrauma . 2021 May; 38(19):2772-2776. PMID: 34002636
The benefits of therapeutic hypothermia (TH) in severe traumatic brain injury (sTBI) have been long debated. In 2018, the POLAR study, a high-quality international trial, appeared to end the debate...
5.
Bidirectional Relationship Between Reduced Blood pH and Acute Pancreatitis: A Translational Study of Their Noxious Combination
Rumbus Z, Toth E, Poto L, Vincze A, Veres G, Czako L, et al.
Front Physiol . 2018 Oct; 9:1360. PMID: 30327613
Acute pancreatitis (AP) is often accompanied by alterations in the acid-base balance, but how blood pH influences the outcome of AP is largely unknown. We studied the association between blood...
6.
Therapeutic Whole-Body Hypothermia Reduces Death in Severe Traumatic Brain Injury if the Cooling Index Is Sufficiently High: Meta-Analyses of the Effect of Single Cooling Parameters and Their Integrated Measure
Olah E, Poto L, Hegyi P, Szabo I, Hartmann P, Solymar M, et al.
J Neurotrauma . 2018 Apr; 35(20):2407-2417. PMID: 29681213
Therapeutic hypothermia was investigated repeatedly as a tool to improve the outcome of severe traumatic brain injury (TBI), but previous clinical trials and meta-analyses found contradictory results. We aimed to...
7.
The Neurokinin-1 Receptor Contributes to the Early Phase of Lipopolysaccharide-Induced Fever Stimulation of Peripheral Cyclooxygenase-2 Protein Expression in Mice
Pakai E, Tekus V, Zsiboras C, Rumbus Z, Olah E, Keringer P, et al.
Front Immunol . 2018 Feb; 9:166. PMID: 29459872
Neurokinin (NK) signaling is involved in various inflammatory processes. A common manifestation of systemic inflammation is fever, which is usually induced in animal models with the administration of bacterial lipopolysaccharide...