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Emma L B Soldner

Explore the profile of Emma L B Soldner including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 300
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Recent Articles
1.
Hartz A, Rempe R, Soldner E, Pekcec A, Schlichtiger J, Kryscio R, et al.
FASEB J . 2019 Oct; 33(12):14281-14295. PMID: 31661303
Blood-brain barrier dysfunction in epilepsy contributes to seizures and resistance to antiseizure drugs. Reports show that seizures increase brain glutamate levels, leading to barrier dysfunction. One component of barrier dysfunction...
2.
Soldner E, Hartz A, Akanuma S, Pekcec A, Doods H, Kryscio R, et al.
FASEB J . 2019 Oct; 33(12):13966-13981. PMID: 31638830
The cause of antiseizure drug (ASD) resistance in epilepsy is poorly understood. Here, we focus on the transporter P-glycoprotein (P-gp) that is partly responsible for limited ASD brain uptake, which...
3.
Rempe R, Hartz A, Soldner E, Sokola B, Alluri S, Abner E, et al.
J Neurosci . 2018 Apr; 38(18):4301-4315. PMID: 29632167
The blood-brain barrier is dysfunctional in epilepsy, thereby contributing to seizure genesis and resistance to antiseizure drugs. Previously, several groups reported that seizures increase brain glutamate levels, which leads to...
4.
Hartz A, Pekcec A, Soldner E, Zhong Y, Schlichtiger J, Bauer B
Mol Pharm . 2017 Feb; 14(4):999-1011. PMID: 28195743
A cure for epilepsy is currently not available, and seizure genesis, seizure recurrence, and resistance to antiseizure drugs remain serious clinical problems. Studies show that the blood-brain barrier is altered...
5.
Hartz A, Bauer B, Soldner E, Wolf A, Boy S, Backhaus R, et al.
Stroke . 2011 Nov; 43(2):514-23. PMID: 22116809
Background And Purpose: Cerebral amyloid angiopathy (CAA) is a degenerative disorder characterized by amyloid-β (Aβ) deposition in the blood-brain barrier (BBB). CAA contributes to injuries of the neurovasculature including lobar...
6.
Heltemes A, Gingery A, Soldner E, Bozadjieva N, Jahr K, Johnson B, et al.
Exp Biol Med (Maywood) . 2010 Jun; 235(7):892-9. PMID: 20558843
Although small size at birth is associated with hypertension and associated co-morbidities such as insulin resistance and type II diabetes mellitus, many of the animal models employed to simulate this...
7.
Gingery A, Soldner E, Heltemes A, Nelson A, Bozadjieva N
J Physiol . 2009 Dec; 587(Pt 23):5521-2. PMID: 19959551
No abstract available.