Emma E Vincent
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Explore the profile of Emma E Vincent including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Alduhayh S, Laskar R, Jiang X, Zhu Z, Vincent E, Constantinescu A, et al.
Cancer Epidemiol Biomarkers Prev
. 2025 Feb;
PMID: 39982694
Background: Tumor immunosurveillance theory supports that allergic conditions could decrease cancer risk. However, observational evidence yielded inconsistent results for the association between allergic diseases and colorectal cancer risk. We used...
2.
Lee M, Hatcher C, Hazelwood E, Goudswaard L, Tsilidis K, Vincent E, et al.
Int J Epidemiol
. 2025 Jan;
54(1).
PMID: 39846783
Background: Adiposity is an established risk factor for colorectal cancer (CRC). The pathways underlying this relationship, and specifically the role of circulating proteins, are unclear. Methods: Utilizing two-sample univariable Mendelian...
3.
Wu X, Ying H, Yang Q, Yang Q, Liu H, Ding Y, et al.
Nat Commun
. 2024 Oct;
15(1):9302.
PMID: 39468075
Immunity has shown potentials in informing drug development for cardiometabolic diseases, such as type 2 diabetes (T2D) and coronary artery disease (CAD). Here, we performed a transcriptome-wide Mendelian randomization (MR)...
4.
Hazelwood E, Manzano C, Vincent E, Albanes D, Bishop D, Le Marchand L, et al.
Cancer Epidemiol Biomarkers Prev
. 2024 Oct;
33(12):1727-1732.
PMID: 39361354
Background: Epidemiological and laboratory-based studies have provided conflicting evidence for a role of ghrelin in colorectal cancer development. We conducted two-sample Mendelian randomization (MR) analyses to evaluate evidence for an...
5.
Legge D, Collard T, Stanko E, Hoskin A, Holt A, Bull C, et al.
Mol Metab
. 2024 Sep;
90:102037.
PMID: 39332495
Colorectal cancer (CRC) is a multi-stage process initiated through the formation of a benign adenoma, progressing to an invasive carcinoma and finally metastatic spread. Tumour cells must adapt their metabolism...
6.
Bojko J, Kollareddy M, Szemes M, Bellamy J, Poon E, Moukachar A, et al.
Cancer Lett
. 2024 Sep;
604:217263.
PMID: 39313128
Approximately 50 % of poor prognosis neuroblastomas arise due to MYCN over-expression. We previously demonstrated that MYCN and PRMT5 proteins interact and PRMT5 knockdown led to apoptosis of MYCN-amplified (MNA)...
7.
Constantinescu A, Hughes D, Bull C, Fleming K, Mitchell R, Zheng J, et al.
Hum Genomics
. 2024 Mar;
18(1):26.
PMID: 38491524
Background: 'Benign ethnic neutropenia' (BEN) is a heritable condition characterized by lower neutrophil counts, predominantly observed in individuals of African ancestry, and the genetic basis of BEN remains a subject...
8.
Farook M, Croxford Z, Morgan S, Horlock A, Holt A, Rees A, et al.
Mol Metab
. 2024 Feb;
81:101900.
PMID: 38354856
The pyruvate transporter MPC1 (mitochondrial pyruvate carrier 1) acts as a tumour-suppressor, loss of which correlates with a pro-tumorigenic phenotype and poor survival in several tumour types. In high-grade serous...
9.
Bull C, Hazelwood E, Legge D, Corbin L, Richardson T, Lee M, et al.
EBioMedicine
. 2024 Jan;
100:104977.
PMID: 38290287
Background: Type 2 diabetes is associated with higher risk of several cancer types. However, the biological intermediates driving this relationship are not fully understood. As novel interventions for treating and...
10.
Bull C, Hazelwood E, Bell J, Tan V, Constantinescu A, Borges C, et al.
Elife
. 2023 Dec;
12.
PMID: 38127078
Background: Recognizing the early signs of cancer risk is vital for informing prevention, early detection, and survival. Methods: To investigate whether changes in circulating metabolites characterize the early stages of...