Emily Streaker
Overview
Explore the profile of Emily Streaker including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
212
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0
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Recent Articles
1.
Puri V, Streaker E, Prabakaran P, Zhu Z, Dimitrov D
MAbs
. 2013 Jun;
5(4):533-9.
PMID: 23765162
Combinatory antibody library display technologies have been invented and successfully implemented for the selection and engineering of therapeutic antibodies. Precise targeting of important epitopes on the protein of interest is...
2.
Gong R, Wang Y, Ying T, Feng Y, Streaker E, Prabakaran P, et al.
Mol Pharm
. 2013 May;
10(7):2642-52.
PMID: 23641816
Isolated human immunoglobulin G (IgG) CH2 domains are promising scaffolds for novel candidate therapeutics. Unlike other human IgG domains, CH2 is not involved in strong interchain interactions, and isolated CH2...
3.
Prabakaran P, Zhu Z, Chen W, Gong R, Feng Y, Streaker E, et al.
Front Microbiol
. 2012 Aug;
3:277.
PMID: 22876240
Our understanding of how antibodies are generated and function could help develop effective vaccines and antibody-based therapeutics against viruses such as HIV-1, SARS coronavirus (SARS CoV), and Hendra and Nipah...
4.
Prabakaran P, Chen W, Singarayan M, Stewart C, Streaker E, Feng Y, et al.
Immunogenetics
. 2011 Dec;
64(5):337-50.
PMID: 22200891
Human cord blood cell-derived IgM antibodies are important for the neonate immune responses and construction of germline-based immunoglobulin libraries. Several previous studies of a relatively small number of sequences found...
5.
Prabakaran P, Streaker E, Chen W, Dimitrov D
BMC Res Notes
. 2011 Oct;
4:404.
PMID: 21992227
Background: 454 sequencing is currently the method of choice for sequencing of antibody repertoires and libraries containing large numbers (106 to 1012) of different molecules with similar frameworks and variable...
6.
Zhu Z, Qin H, Chen W, Zhao Q, Shen X, Schutte R, et al.
J Virol
. 2011 Sep;
85(21):11401-8.
PMID: 21880764
The genes encoding broadly HIV-1-neutralizing human monoclonal antibodies (MAbs) are highly divergent from their germ line counterparts. We have hypothesized that such high levels of somatic hypermutation could pose a...
7.
Yuan T, Li J, Zhang Y, Wang Y, Streaker E, Dimitrov D, et al.
Vaccine
. 2011 Aug;
29(40):6903-10.
PMID: 21807049
Broadly neutralizing antibodies (bnAbs) are likely to be a key component of protective immunity conferred by an effective HIV-1 vaccine. We and others have reported that putative human germline predecessors...
8.
Feng Y, Xiao X, Zhu Z, Streaker E, Ho M, Pastan I, et al.
Mol Cancer Ther
. 2009 May;
8(5):1113-8.
PMID: 19417159
Mesothelin is a potential new target for cancer immunotherapy because it is present at relatively low levels only in mesothelial cells of pleura, peritoneum, and pericardium of healthy people, but...
9.
Zhao H, Streaker E, Pan W, Beckett D
Biochemistry
. 2007 Nov;
46(47):13667-76.
PMID: 17973495
Assembly of the transcription repression complex at the Escherichia coli biotin biosynthetic operon occurs via coupled protein-protein and protein-DNA interactions in which the holoBirA dimer binds to the forty base...