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Emily Karbarz

Explore the profile of Emily Karbarz including associated specialties, affiliations and a list of published articles. Areas
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Articles 3
Citations 37
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Recent Articles
1.
Robles O, Jackson J, Marshall L, Talay O, Chian D, Cutler G, et al.
J Med Chem . 2020 Jul; 63(15):8584-8607. PMID: 32667798
The C-C chemokine receptor 4 (CCR4) is broadly expressed on regulatory T cells (T) as well as other circulating and tissue-resident T cells. T can be recruited to the tumor...
2.
Leger P, Hu D, Biannic B, Bui M, Han X, Karbarz E, et al.
J Med Chem . 2020 Apr; 63(10):5398-5420. PMID: 32302140
USP7 is a promising target for cancer therapy as its inhibition is expected to decrease function of oncogenes, increase tumor suppressor function, and enhance immune function. Using a structure-based drug...
3.
Jackson J, Ketcham J, Younai A, Abraham B, Biannic B, Beck H, et al.
J Med Chem . 2019 Jul; 62(13):6190-6213. PMID: 31259550
Recruitment of suppressive CD4 FOXP3 regulatory T cells (T) to the tumor microenvironment (TME) has the potential to weaken the antitumor response in patients receiving treatment with immuno-oncology (IO) agents....