Emily J Reinhard
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Explore the profile of Emily J Reinhard including associated specialties, affiliations and a list of published articles.
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4
Citations
42
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Recent Articles
1.
Packiarajan M, Coate H, Desai M, Jimenez H, Reinhard E, Jubian V, et al.
Bioorg Med Chem Lett
. 2011 Sep;
21(21):6500-4.
PMID: 21924902
Synthesis, SAR and physico-chemical properties of an alkyl aminothiazole series 8 and 16 are described. 2-Pyridylaminothiazole based compounds such as 8c and 16a exhibit high affinity at the NPY(5) receptor...
2.
Discovery of potent, nonsystemic apical sodium-codependent bile acid transporter inhibitors (Part 2)
Huang H, Tremont S, Lee L, Keller B, Carpenter A, Wang C, et al.
J Med Chem
. 2005 Sep;
48(18):5853-68.
PMID: 16134951
In the preceding paper several compounds were reported as potent apical sodium-codependent bile acid transporter (ASBT) inhibitors. Since the primary site for active bile acid reabsorption is via ASBT, which...
3.
Discovery of potent, nonsystemic apical sodium-codependent bile acid transporter inhibitors (Part 1)
Tremont S, Lee L, Huang H, Keller B, Banerjee S, Both S, et al.
J Med Chem
. 2005 Sep;
48(18):5837-52.
PMID: 16134950
Elevated plasma levels of low-density lipoprotein (LDL) cholesterol are a major risk factor for atherosclerosis leading to coronary artery disease (CAD), which remains the main cause of mortality in Western...
4.
Reinhard E, Wang J, Durley R, Fobian Y, Grapperhaus M, Hickory B, et al.
J Med Chem
. 2003 May;
46(11):2152-68.
PMID: 12747787
A novel series of substituted N-[3-(1,1,2,2-tetrafluoroethoxy)benzyl]-N-(3-phenoxyphenyl)-trifluoro-3-amino-2-propanols is described which potently and reversibly inhibit cholesteryl ester transfer protein (CETP). Starting from the initial lead 1, various substituents were introduced into the...