Emily C A Goodall
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Explore the profile of Emily C A Goodall including associated specialties, affiliations and a list of published articles.
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11
Citations
210
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Recent Articles
1.
Rooke J, Goodall E, Pullela K, Da Costa R, Martinelli N, Smith C, et al.
mBio
. 2024 Sep;
15(10):e0331923.
PMID: 39287440
is a globally disseminated pathogen that is the cause of over 100 million infections per year. The resulting diseases are dependent upon host susceptibility and the infecting serovar. As serovar...
2.
Butler M, Vollmer W, Goodall E, Capon R, Henderson I, Blaskovich M
ACS Infect Dis
. 2024 Jul;
10(10):3440-3474.
PMID: 39018341
There is a lack of new antibiotics to combat drug-resistant bacterial infections that increasingly threaten global health. The current pipeline of clinical-stage antimicrobials is primarily populated by "new and improved"...
3.
Warner I, Kok W, Martinelli N, Yang Z, Goodall E, Henderson I
Microbiology (Reading)
. 2023 Nov;
169(11).
PMID: 37909267
Genetic screens are a key tool for linking phenotype and genotype. Transposon mutagenesis was one of the first genetic methodologies to associate genetic loci with phenotypes. The advent of next-generation...
4.
Goodall E, Azevedo Antunes C, Moller J, Sangal V, Torres V, Gray J, et al.
PLoS Genet
. 2023 Apr;
19(4):e1010737.
PMID: 37099600
Diphtheria is a respiratory disease caused by Corynebacterium diphtheriae. While the toxin-based vaccine has helped control outbreaks of the disease since the mid-20th century there has been an increase in...
5.
Yu Z, Goodall E, Henderson I, Guo J
Adv Sci (Weinh)
. 2022 Nov;
10(2):e2203260.
PMID: 36424175
Bacterial cell filamentation is a morphological change wherein cell division is blocked, which can improve bacterial survival under unfavorable conditions (e.g., antibiotic stress that causes DNA damage). As an extrachromosomal...
6.
Roth M, Goodall E, Pullela K, Jaquet V, Francois P, Henderson I, et al.
Antioxidants (Basel)
. 2022 Oct;
11(10).
PMID: 36290776
Hydrogen peroxide (HO) is a common effector of defense mechanisms against pathogenic infections. However, bacterial factors involved in HO tolerance remain unclear. Here we used transposon-directed insertion-site sequencing (TraDIS), a...
7.
Goodall E, Morris F, McKeand S, Sullivan R, Warner I, Sheehan E, et al.
Microbiol Spectr
. 2022 Jul;
10(4):e0083322.
PMID: 35856675
In recent years the availability of genome sequence information has grown logarithmically resulting in the identification of a plethora of uncharacterized genes. To address this gap in functional annotation, many...
8.
Goodall E, Isom G, Rooke J, Pullela K, Icke C, Yang Z, et al.
PLoS Genet
. 2021 Dec;
17(12):e1009586.
PMID: 34941903
The cell envelope is essential for viability in all domains of life. It retains enzymes and substrates within a confined space while providing a protective barrier to the external environment....
9.
Winkle M, Hernandez-Rocamora V, Pullela K, Goodall E, Martorana A, Gray J, et al.
mBio
. 2021 May;
12(3).
PMID: 33947763
Gram-negative bacteria have a unique cell envelope with a lipopolysaccharide-containing outer membrane that is tightly connected to a thin layer of peptidoglycan. The tight connection between the outer membrane and...
10.
Pathogenic Differences of Type 1 Restriction-Modification Allele Variants in Experimental Meningitis
Zbinden F, De Ste Croix M, Grandgirard D, Haigh R, Vacca I, Zamudio R, et al.
Front Cell Infect Microbiol
. 2020 Nov;
10:590657.
PMID: 33194838
meningoencephalitis has a mortality rate of up to 50% and neurofunctional sequelae are common. Type I restriction-modification systems (RMS) are capable of adding methyl groups to the host genome. Some...