Emily A Day
Overview
Explore the profile of Emily A Day including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
1268
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Recent Articles
1.
Rehill A, McCluskey S, Ledwith A, Ryan T, Unlu B, Leon G, et al.
Sci Adv
. 2025 Mar;
11(10):eads0105.
PMID: 40053582
The pathogenic basis for increased thrombotic risk in individuals with inflammatory diseases is poorly understood. Myeloid cell "trained immunity" describes persistent innate immune cell memory arising from prior exposure to...
2.
Desjardins E, Day E, Scott J, Steinberg G
Methods Mol Biol
. 2025 Feb;
2882:121-137.
PMID: 39992507
Fatty acids are utilized to maintain cellular energy/adenine nucleotide balance under times of energetic stress such as during endurance exercise or fasting. It has long been recognized that fatty acids...
3.
Zotta A, Toller-Kawahisa J, Palsson-McDermott E, OCarroll S, Henry O, Day E, et al.
Sci Adv
. 2025 Jan;
11(4):eadq7307.
PMID: 39841829
The cytokine interleukin-10 (IL-10) limits the immune response and promotes resolution of acute inflammation. Because of its immunosuppressive effects, IL-10 up-regulation is a common feature of tumor progression and metastasis....
4.
OCarroll S, Peace C, Toller-Kawahisa J, Min Y, Hooftman A, Charki S, et al.
Nat Metab
. 2024 Dec;
7(1):228.
PMID: 39668260
No abstract available.
5.
Douglas A, Stevens B, Rendas M, Kane H, Lynch E, Kunkemoeller B, et al.
Nature
. 2024 Oct;
636(8041):206-214.
PMID: 39478228
The circadian rhythm of the immune system helps to protect against pathogens; however, the role of circadian rhythms in immune homeostasis is less well understood. Innate T cells are tissue-resident...
6.
OCarroll S, Peace C, Toller-Kawahisa J, Min Y, Hooftman A, Charki S, et al.
Nat Metab
. 2024 Oct;
6(11):2060-2069.
PMID: 39406969
Itaconate is one of the most highly upregulated metabolites in inflammatory macrophages and has been shown to have immunomodulatory properties. Here, we show that itaconate promotes type I interferon production...
7.
Scott B, Day E, OBrien K, Scanlan J, Cromwell G, Scannail A, et al.
Nat Metab
. 2024 Mar;
6(4):651-658.
PMID: 38499765
Metformin, a widely used first-line treatment for type 2 diabetes (T2D), is known to reduce blood glucose levels and suppress appetite. Here we report a significant elevation of the appetite-suppressing...
8.
Day E, Townsend L, Rehal S, Batchuluun B, Wang D, Morrow M, et al.
iScience
. 2023 Nov;
26(11):108269.
PMID: 38026185
Atherosclerotic cardiovascular disease is characterized by both chronic low-grade inflammation and dyslipidemia. The AMP-activated protein kinase (AMPK) inhibits cholesterol synthesis and dampens inflammation but whether pharmacological activation reduces atherosclerosis is...
9.
Diskin C, Day E, Henry O, Toller-Kawahisa J, ONeill L
J Immunol
. 2023 Aug;
211(6):1032-1041.
PMID: 37578391
Annexin A1 is a key anti-inflammatory effector protein that is involved in the anti-inflammatory effects of glucocorticoids. 4-Octyl itaconate (4-OI), a derivative of the endogenous metabolite itaconate, which is abundantly...
10.
Ryan T, Hooftman A, Rehill A, Johansen M, O Brien E, Toller-Kawahisa J, et al.
Nat Commun
. 2023 Jul;
14(1):4374.
PMID: 37474527
No abstract available.