Emile Barrias
Overview
Explore the profile of Emile Barrias including associated specialties, affiliations and a list of published articles.
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9
Citations
49
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Recent Articles
1.
Nunes Lemes L, Magoulas G, Oliveira A, Barrias E, de Camargo Nascente L, Granado R, et al.
ACS Infect Dis
. 2023 Jun;
9(7):1334-1345.
PMID: 37307287
Six new ether phospholipid analogues encompassing constituents from cashew nut shell liquid as the lipid portion were synthesized in an effort to valorize byproducts of the cashew industry toward the...
2.
Roussaki M, Magoulas G, Fotopoulou T, Santarem N, Barrias E, Pohner I, et al.
Bioorg Chem
. 2023 May;
138:106615.
PMID: 37244229
A series of nine novel ether phospholipid-dinitroaniline hybrids were synthesized in an effort to deliver more potent antiparasitic agents with improved safety profile compared to miltefosine. The compounds were evaluated...
3.
Cunha de Souza C, de Azevedo-Franca J, Barrias E, Cavalcante S, Vieira E, da Costa Ferreira A, et al.
J Inorg Biochem
. 2022 Nov;
239:112047.
PMID: 36428157
Currently the only drug available to treat Chagas disease in Brazil is benznidazole (BZN). Therefore, there is an urgent need to discover and develop new anti- Trypanosoma cruzi candidates. In...
4.
de Azevedo-Franca J, Barrias E, Franco C, Villarreal W, Vieira E, da Costa Ferreira A, et al.
J Inorg Biochem
. 2022 May;
233:111834.
PMID: 35500350
A series of new transition metal coordination polymers, [Zn(Ac)(FLZ)] (1) [Zn(FLZ)(Cl)] (2), {[Zn(FLZ)](NO)} (3), [Cu(FLZ)(CH₃COO)] (4) {[Cu(FLZ)Cl]} (5) and {[Cu(FLZ)](NO)} (6), were synthesized by the reaction of fluconazole (FLZ) with...
5.
Magoulas G, Afroudakis P, Georgikopoulou K, Roussaki M, Borsari C, Fotopoulou T, et al.
Molecules
. 2021 Jul;
26(14).
PMID: 34299479
A library of seventeen novel ether phospholipid analogues, containing 5-membered heterocyclic rings (1,2,3-triazolyl, isoxazolyl, 1,3,4-oxadiazolyl and 1,2,4-oxadiazolyl) in the lipid portion were designed and synthesized aiming to identify optimised miltefosine...
6.
Portes J, Barrias E, Travassos R, Attias M, De Souza W
Front Cell Infect Microbiol
. 2020 Jul;
10:294.
PMID: 32714877
, the causative agent of toxoplasmosis, is an obligate intracellular protozoan parasite. can invade and multiply inside any nucleated cell of a wide range of homeothermic hosts. The canonical process...
7.
de Azevedo-Franca J, Granado R, Teixeira de Macedo Silva S, Santos-Silva G, Scapin S, Borba-Santos L, et al.
Antimicrob Agents Chemother
. 2020 Mar;
64(5).
PMID: 32152072
The new complexes Zn(ITZ)Cl (1) and Zn(ITZ)(OH) (2) were synthetized by a reaction of itraconazole with their respective zinc salts under reflux. These Zn-ITZ complexes were characterized by elemental analyses,...
8.
Barrias E, Reignault L, Calogeropoulou T, De Souza W
Exp Parasitol
. 2019 Sep;
206:107730.
PMID: 31494215
Phospholipids are the main component of membranes and are responsible for cell integrity. Alkylphospholipid analogues (APs) were first designed as antitumoral agents and were later tested against different cell types....
9.
Barrias E, Reignault L, de Carvalho T, De Souza W
Acta Trop
. 2019 Jun;
199:105057.
PMID: 31202818
A number of intracellular pathogens are internalized by host cells via multiple endocytic pathways, including Trypanosoma cruzi, the etiological agent of Chagas disease. Clathrin-mediated endocytosis is the most characterized endocytic...