Emebet Mengesha
Overview
Explore the profile of Emebet Mengesha including associated specialties, affiliations and a list of published articles.
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40
Citations
1078
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Recent Articles
1.
Kang L, Sarullo K, Marsh J, Lu L, Khonde P, Ma C, et al.
EBioMedicine
. 2024 Nov;
110:105440.
PMID: 39536395
Background: Alterations in ileal Paneth cell (PC) density have been described in gut inflammatory diseases such as Crohn's disease (CD) and could be used as a biomarker for disease prognosis....
2.
Sun S, Hodel M, Wang X, De Vicente J, Haritunians T, Debebe A, et al.
Sci Immunol
. 2024 Nov;
9(101):eadi7907.
PMID: 39514635
polymorphisms (G2019S/N2081D) that increase susceptibility to Parkinson's disease and Crohn's disease (CD) lead to LRRK2 kinase hyperactivity and suppress autophagy. This connection suggests that LRRK2 kinase inhibition, a therapeutic strategy...
3.
Fu Q, Vegesna M, Sundararaman N, Damoc E, Arrey T, Pashkova A, et al.
Angew Chem Int Ed Engl
. 2024 Oct;
63(52):e202409446.
PMID: 39432331
Clinical biomarker development has been stymied by inaccurate protein quantification from mass spectrometry (MS) discovery data and a prolonged validation process. To mitigate these issues, we created the Targeted Extraction...
4.
Hernandez-Rocha C, Turpin W, Borowski K, Stempak J, Sabic K, Gettler K, et al.
Clin Gastroenterol Hepatol
. 2024 Jul;
23(4):612-620.e10.
PMID: 38969076
Background & Aims: Investigating the tissue-associated microbiota after surgically induced remission may help to understand the mechanisms initiating intestinal inflammation in Crohn's disease. Methods: Patients with Crohn's disease undergoing ileocolic...
5.
Ma C, Haritunians T, Gremida A, Syal G, Shah J, Yang S, et al.
J Crohns Colitis
. 2024 Jul;
PMID: 38953127
Background & Aims: Biomarkers that integrate genetic and environmental factors and predict outcome in complex immune diseases such as inflammatory bowel disease (IBD; including Crohn's disease [CD] and ulcerative colitis...
6.
Fu Q, Vegesna M, Sundararaman N, Damoc E, Arrey T, Pashkova A, et al.
bioRxiv
. 2024 Apr;
PMID: 38562888
Clinical biomarker development has been stymied by inaccurate protein quantification from mass spectrometry (MS) discovery data and a prolonged validation process. To mitigate these issues, we created the Targeted Extraction...
7.
Khrom M, Long M, Dube S, Robbins L, Botwin G, Yang S, et al.
Gastroenterology
. 2024 Mar;
167(2):315-332.
PMID: 38490347
Background & Aims: Patients with inflammatory bowel disease (IBD) frequently develop extraintestinal manifestations (EIMs) that contribute substantially to morbidity. We assembled the largest multicohort data set to date to investigate...
8.
Malique A, Sun S, Chandwe K, Amadi B, Haritunians T, Jain U, et al.
Sci Transl Med
. 2024 Jan;
16(728):eabq4145.
PMID: 38170788
Environmental enteric dysfunction (EED) is a diffuse small bowel disorder associated with poor growth, inadequate responses to oral vaccines, and nutrient malabsorption in millions of children worldwide. We identify loss...
9.
Hernandez-Rocha C, Walshe M, Birch S, Sabic K, Korie U, Chasteau C, et al.
J Crohns Colitis
. 2023 Nov;
18(4):615-627.
PMID: 37976264
Background And Aims: Multiple factors are suggested to place Crohn's disease patients at risk of recurrence after ileocolic resection with conflicting associations. We aimed to identify clinical predictors of recurrence...
10.
Lee Y, Li D, Mujukian A, Debbas P, Hampton M, Mengesha E, et al.
Inflamm Bowel Dis
. 2023 Sep;
30(8):1430-1434.
PMID: 37773982
No abstract available.