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Elizabeth R Gavis

Explore the profile of Elizabeth R Gavis including associated specialties, affiliations and a list of published articles. Areas
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Articles 58
Citations 1748
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Recent Articles
1.
Kilwein M, Miller P, Lee K, Osterfield M, Mogilner A, Shvartsman S, et al.
Curr Biol . 2025 Mar; PMID: 40049172
Germline-soma segregation is crucial for fertility. Primordial germ cells (PGCs) arise early in development and are the very first cells to form in the Drosophila embryo. At the time of...
2.
Siddiqui N, Karaiskakis A, Goldman A, Eagle W, Low T, Luo H, et al.
Sci Adv . 2024 Apr; 10(15):eadg7894. PMID: 38608012
During Drosophila oogenesis, the Oskar (OSK) RNA binding protein (RBP) determines the amount of germ plasm that assembles at the posterior pole of the oocyte. Here, we identify mechanisms that...
3.
Eichler C, Li H, Grunberg M, Gavis E
PLoS Genet . 2023 Aug; 19(8):e1010877. PMID: 37624861
Localization of oskar mRNA to the posterior of the Drosophila oocyte is essential for abdominal patterning and germline development. oskar localization is a multi-step process involving temporally and mechanistically distinct...
4.
Warden M, DeRose E, Tamayo J, Mueller G, Gavis E, Hall T
Nucleic Acids Res . 2023 Jul; 51(16):8836-8849. PMID: 37427795
The Drosophila melanogaster protein Glorund (Glo) represses nanos (nos) translation and uses its quasi-RNA recognition motifs (qRRMs) to recognize both G-tract and structured UA-rich motifs within the nos translational control...
5.
Breznak S, Peng Y, Deng L, Kotb N, Flamholz Z, Rapisarda I, et al.
Sci Adv . 2023 Jun; 9(25):eade5492. PMID: 37343092
Stem cells in many systems, including germline stem cells (GSCs), increase ribosome biogenesis and translation during terminal differentiation. Here, we show that the H/ACA small nuclear ribonucleoprotein (snRNP) complex that...
6.
Hakes A, Gavis E
PLoS Biol . 2023 Apr; 21(4):e3002069. PMID: 37053289
Compartmentalization of RNAs and proteins into membraneless structures called granules is a ubiquitous mechanism for organizing and regulating cohorts of RNAs. Germ granules are ribonucleoprotein (RNP) assemblies required for germline...
7.
Siddiqui N, Karaiskakis A, Goldman A, Eagle W, Smibert C, Gavis E, et al.
bioRxiv . 2023 Mar; PMID: 36909513
During Drosophila oogenesis, the Oskar (OSK) RNA-binding protein (RBP) determines the amount of germ plasm that assembles at the posterior pole of the oocyte. Here we identify the mechanisms that...
8.
Li H, Gavis E
G3 (Bethesda) . 2022 Sep; 12(11). PMID: 36102801
MicroRNAs are enriched in neurons and play important roles in dendritic spine development and synaptic plasticity. MicroRNA activity is controlled by a wide range of RNA-binding proteins. FMRP, a highly...
9.
Peng Y, Gavis E
Nucleic Acids Res . 2022 Jun; 50(12):7067-7083. PMID: 35699205
Translational control of maternal mRNAs generates spatial and temporal patterns of protein expression necessary to begin animal development. Translational repression of unlocalized nanos (nos) mRNA in late-stage Drosophila oocytes by...
10.
Li H, Gavis E
Development . 2022 May; 149(10). PMID: 35502752
Dendritic arbor development is a complex, highly regulated process. Post-transcriptional regulation mediated by RNA-binding proteins plays an important role in neuronal dendrite morphogenesis by delivering on-site, on-demand protein synthesis. Here,...