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Elizabeth M Wagner

Explore the profile of Elizabeth M Wagner including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Eldridge L, Wagner E
J Physiol . 2018 Jul; 597(4):1023-1032. PMID: 30022479
Both systemic (tracheal and bronchial) and pulmonary circulations perfuse the lung. However, documentation of angiogenesis of either is complicated by the presence of the other. Well-documented angiogenesis of the systemic...
2.
Moldobaeva A, Zhong Q, Eldridge L, Wagner E
Physiol Rep . 2018 Jun; 6(11):e13721. PMID: 29894584
The importance of myeloid cells in promoting neovascularization has been shown in a number of pathological settings in several organs. However, the specific role of macrophages in promoting systemic angiogenesis...
3.
Lanza G, Jenkins J, Schmieder A, Moldobaeva A, Cui G, Zhang H, et al.
Theranostics . 2017 Jan; 7(2):377-389. PMID: 28042341
Although angiogenesis is a hallmark feature of asthmatic inflammatory responses, therapeutic anti-angiogenesis interventions have received little attention. Assess the effectiveness of anti-angiogenic Sn2 lipase-labile prodrugs delivered via αβ-micellar nanotherapy to...
4.
Moldobaeva A, Jenkins J, Zhong Q, Wagner E
Angiogenesis . 2016 Oct; 20(1):73-84. PMID: 27787629
Although bronchial angiogenesis has been well documented in allergic asthma, lymphangiogenesis has not been widely studied. Therefore, we evaluated changes in lung lymphatics in a rat model of allergen-induced asthma...
5.
Eldridge L, Moldobaeva A, Zhong Q, Jenkins J, Snyder M, Brown R, et al.
Cancer Res . 2016 Aug; 76(20):5962-5969. PMID: 27569207
Angiogenesis is vital for tumor growth but in well-vascularized organs such as the lung its importance is unclear. This situation is complicated by the fact that the lung has two...
6.
Zhong Q, Jenkins J, Moldobaeva A, DAlessio F, Wagner E
Am J Respir Cell Mol Biol . 2015 Aug; 54(3):394-401. PMID: 26244419
Lymphocytes have been shown to modulate angiogenesis. Our previous work showed that T regulatory (Treg) cell depletion prevented angiogenesis. In the present study, we sought to examine T-cell populations during...
7.
DAlessio F, Zhong Q, Jenkins J, Moldobaeva A, Wagner E
Am J Respir Cell Mol Biol . 2014 Oct; 52(5):603-10. PMID: 25275926
Angiogenesis in ischemic organs is modulated by immune cells. Systemic neovascularization of the ischemic lung requires macrophages, with chemokines playing a central role in new vessel growth. Because regulatory T...
8.
Moldobaeva A, Rentsendorj O, Jenkins J, Wagner E
PLoS One . 2014 Sep; 9(9):e106092. PMID: 25181540
The process of leukocyte recruitment to the airways in real time has not been extensively studied, yet airway inflammation persists as a major contributor to lung pathology. We showed previously...
9.
Wagner E, Jenkins J, Schmieder A, Eldridge L, Zhang Q, Moldobaeva A, et al.
Angiogenesis . 2014 Aug; 18(1):1-11. PMID: 25149641
Expanded and aberrant bronchial vascularity, a prominent feature of the chronic asthmatic airway, might explain persistent airway wall edema and sustained leukocyte recruitment. Since it is well established that there...
10.
Brown M, Hunt W, Noe J, Rush N, Schweitzer K, Leece T, et al.
Pulm Circ . 2014 Jul; 4(2):260-8. PMID: 25006445
Abnormal lung microvascular endothelial vascular barrier function may contribute to pulmonary inflammation, such as that occurring during inhalation of cigarette smoke (CS). Cystic fibrosis transmembrane conductance regulator (CFTR), an anion...