Aigul Moldobaeva
Overview
Explore the profile of Aigul Moldobaeva including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
352
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0
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Recent Articles
1.
Angeles-Lopez Q, Rodriguez-Lopez J, Agudelo Garcia P, Calyeca J, Alvarez D, Bueno M, et al.
JCI Insight
. 2025 Feb;
10(3).
PMID: 39927460
Idiopathic pulmonary fibrosis (IPF) is an age-related interstitial lung disease, characterized by inadequate alveolar regeneration and ectopic bronchiolization. While some molecular pathways regulating lung progenitor cells have been described, the...
2.
Dagher R, Moldobaeva A, Gubbins E, Clark S, Alfajaro M, Wilen C, et al.
Stem Cells
. 2024 Jan;
42(3):230-250.
PMID: 38183264
Chronic inflammation and dysregulated repair mechanisms after epithelial damage have been implicated in chronic obstructive pulmonary disease (COPD). However, the lack of ex vivo-models that accurately reflect multicellular lung tissue...
3.
Goyanes A, Moldobaeva A, Marimoutou M, Varela L, Wang L, Johnston L, et al.
Am J Respir Cell Mol Biol
. 2020 Jan;
62(4):524-534.
PMID: 31922883
Pulmonary arterial hypertension (PAH) is an incurable disease characterized by disordered and dysfunctional angiogenesis leading to small-vessel loss and an obliterative vasculopathy. The pathogenesis of PAH is not fully understood,...
4.
Moldobaeva A, Zhong Q, Eldridge L, Wagner E
Physiol Rep
. 2018 Jun;
6(11):e13721.
PMID: 29894584
The importance of myeloid cells in promoting neovascularization has been shown in a number of pathological settings in several organs. However, the specific role of macrophages in promoting systemic angiogenesis...
5.
Lanza G, Jenkins J, Schmieder A, Moldobaeva A, Cui G, Zhang H, et al.
Theranostics
. 2017 Jan;
7(2):377-389.
PMID: 28042341
Although angiogenesis is a hallmark feature of asthmatic inflammatory responses, therapeutic anti-angiogenesis interventions have received little attention. Assess the effectiveness of anti-angiogenic Sn2 lipase-labile prodrugs delivered via αβ-micellar nanotherapy to...
6.
Moldobaeva A, Jenkins J, Zhong Q, Wagner E
Angiogenesis
. 2016 Oct;
20(1):73-84.
PMID: 27787629
Although bronchial angiogenesis has been well documented in allergic asthma, lymphangiogenesis has not been widely studied. Therefore, we evaluated changes in lung lymphatics in a rat model of allergen-induced asthma...
7.
Eldridge L, Moldobaeva A, Zhong Q, Jenkins J, Snyder M, Brown R, et al.
Cancer Res
. 2016 Aug;
76(20):5962-5969.
PMID: 27569207
Angiogenesis is vital for tumor growth but in well-vascularized organs such as the lung its importance is unclear. This situation is complicated by the fact that the lung has two...
8.
Zhong Q, Jenkins J, Moldobaeva A, DAlessio F, Wagner E
Am J Respir Cell Mol Biol
. 2015 Aug;
54(3):394-401.
PMID: 26244419
Lymphocytes have been shown to modulate angiogenesis. Our previous work showed that T regulatory (Treg) cell depletion prevented angiogenesis. In the present study, we sought to examine T-cell populations during...
9.
DAlessio F, Zhong Q, Jenkins J, Moldobaeva A, Wagner E
Am J Respir Cell Mol Biol
. 2014 Oct;
52(5):603-10.
PMID: 25275926
Angiogenesis in ischemic organs is modulated by immune cells. Systemic neovascularization of the ischemic lung requires macrophages, with chemokines playing a central role in new vessel growth. Because regulatory T...
10.
Moldobaeva A, Rentsendorj O, Jenkins J, Wagner E
PLoS One
. 2014 Sep;
9(9):e106092.
PMID: 25181540
The process of leukocyte recruitment to the airways in real time has not been extensively studied, yet airway inflammation persists as a major contributor to lung pathology. We showed previously...