Elizabeth I Valoret
Overview
Explore the profile of Elizabeth I Valoret including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
226
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Recent Articles
1.
Preclinical activity of eltrombopag (SB-497115), an oral, nonpeptide thrombopoietin receptor agonist
Erickson-Miller C, Delorme E, Tian S, Hopson C, Landis A, Valoret E, et al.
Stem Cells
. 2008 Nov;
27(2):424-30.
PMID: 19038790
Eltrombopag is a first-in-class, orally bioavailable, small-molecule, nonpeptide agonist of the thrombopoietin receptor (TpoR), which is being developed as a treatment for thrombocytopenia of various etiologies. In vitro studies have...
2.
Bogacheva O, Bogachev O, Menon M, Dev A, Houde E, Valoret E, et al.
J Biol Chem
. 2008 Oct;
283(52):36665-75.
PMID: 18854306
During anemia erythropoiesis is bolstered by several factors including KIT ligand, oncostatin-M, glucocorticoids, and erythropoietin. Less is understood concerning factors that limit this process. Experiments performed using dual-specificity tyrosine-regulated kinase-3...
3.
Prabhakar U, Conway T, Murdock P, Mooney J, Clark S, Hedge P, et al.
DNA Cell Biol
. 2005 Jul;
24(7):410-31.
PMID: 16008510
Administration of endotoxin (LPS) in humans results in profound physiological responses, including activation of peripheral blood mononuclear cells and the release of inflammatory factors. The time course of the response...
4.
Erickson-Miller C, Delorme E, Tian S, Hopson C, Stark K, Giampa L, et al.
Exp Hematol
. 2005 Jan;
33(1):85-93.
PMID: 15661401
Objective: Peptide and other small molecule agonists have been described for several cytokines and growth factors. Hydrazone compounds described here as thrombopoietin receptor agonists were identified as activating STAT proteins...