Elizabeth Conibear
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Explore the profile of Elizabeth Conibear including associated specialties, affiliations and a list of published articles.
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43
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1817
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Recent Articles
1.
Dziurdzik S, Sridhar V, Eng H, Neuman S, Yan J, Davey M, et al.
bioRxiv
. 2025 Feb;
PMID: 39990326
Membrane contact sites between organelles are important for maintaining cellular lipid homeostasis. Members of the recently identified family of bridge-like lipid transfer proteins (BLTPs) span opposing membranes at these contact...
2.
Holme S, Sapia J, Davey M, Vanni S, Conibear E
J Cell Biol
. 2025 Feb;
224(4).
PMID: 39951021
The dynamic addition and removal of long-chain fatty acids modulate protein function and localization. The α/β hydrolase domain-containing (ABHD) 17 enzymes remove acyl chains from membrane-localized proteins such as the...
3.
Shortill S, Frier M, Davey M, Conibear E
Mol Biol Cell
. 2024 Apr;
35(6):ar76.
PMID: 38598303
Endosomal coats incorporate membrane-binding subunits such as sorting nexin (SNX) proteins. The SNX-BAR paralogs Vin1 and Vps5 are respective subunits of the endosomal VINE and retromer complexes whose dimerizing BAR...
4.
Strawn G, Wong R, Young B, Davey M, Nislow C, Conibear E, et al.
Microb Cell Fact
. 2024 Jan;
23(1):36.
PMID: 38287338
The yeast Saccharomyces cerevisiae is widely used as a host cell for recombinant protein production due to its fast growth, cost-effective culturing, and ability to secrete large and complex proteins....
5.
Castro I, Shortill S, Dziurdzik S, Cadou A, Ganesan S, Valenti R, et al.
Elife
. 2022 Nov;
11.
PMID: 36354737
Actively maintained close appositions between organelle membranes, also known as contact sites, enable the efficient transfer of biomolecules between cellular compartments. Several such sites have been described as well as...
6.
Shortill S, Frier M, Wongsangaroonsri P, Davey M, Conibear E
Elife
. 2022 Aug;
11.
PMID: 35938928
Membrane trafficking pathways perform important roles in establishing and maintaining the endosomal network. Retrograde protein sorting from the endosome is promoted by conserved SNX-BAR-containing coat complexes including retromer which enrich...
7.
Shortill S, Frier M, Conibear E
Curr Opin Cell Biol
. 2022 May;
76:102087.
PMID: 35569261
The endolysosomal network consists of highly dynamic membrane-bound compartments that control subcellular degradative and recycling processes. A conserved family of endosomal coat complexes known as SNX-BARs drive the formation of...
8.
Ulengin-Talkish I, Parson M, Jenkins M, Roy J, Shih A, St-Denis N, et al.
Nat Commun
. 2021 Oct;
12(1):6064.
PMID: 34663815
Calcineurin, the conserved protein phosphatase and target of immunosuppressants, is a critical mediator of Ca signaling. Here, to discover calcineurin-regulated processes we examined an understudied isoform, CNAβ1. We show that...
9.
Dziurdzik S, Conibear E
Int J Mol Sci
. 2021 Apr;
22(6).
PMID: 33809364
The conserved VPS13 proteins constitute a new family of lipid transporters at membrane contact sites. These large proteins are suspected to bridge membranes and form a direct channel for lipid...
10.
Dziurdzik S, Bean B, Davey M, Conibear E
Hum Mol Genet
. 2020 Jan;
29(4):635-648.
PMID: 31943017
Mutations in each of the four human VPS13 (VPS13A-D) proteins are associated with distinct neurological disorders: chorea-acanthocytosis, Cohen syndrome, early-onset Parkinson's disease and spastic ataxia. Recent evidence suggests that the...