Elizabeth A Strychalski
Overview
Explore the profile of Elizabeth A Strychalski including associated specialties, affiliations and a list of published articles.
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26
Citations
992
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Recent Articles
1.
Rothschild L, Averesch N, Strychalski E, Moser F, Glass J, Cruz Perez R, et al.
ACS Synth Biol
. 2024 Mar;
13(4):974-997.
PMID: 38530077
The construction of a living organism is a compelling vision. Despite the astonishing technologies developed to modify living cells, building a functioning cell "from scratch" has yet to be accomplished....
2.
Lux M, Strychalski E, Vora G
Synth Biol (Oxf)
. 2023 Nov;
8(1):ysad015.
PMID: 38022745
No abstract available.
3.
Lux M, Strychalski E, Vora G
Synth Biol (Oxf)
. 2023 Nov;
8(1):ysad014.
PMID: 38022744
Reproducibility has been identified as an outstanding challenge in science, and the field of synthetic biology is no exception. Meeting this challenge is critical to allow the transformative technological capabilities...
4.
Taghon G, Strychalski E
Cell Genom
. 2023 Nov;
3(11):100438.
PMID: 38020966
Microbes have long provided us with important capabilities, and the genome engineering of microbes has greatly empowered research and applications in biotechnology. This is especially true with the emergence of...
5.
Schaffter S, Wintenberg M, Murphy T, Strychalski E
ACS Synth Biol
. 2023 May;
12(5):1546-1561.
PMID: 37134273
Cotranscriptionally encoded RNA strand displacement (ctRSD) circuits are an emerging tool for programmable molecular computation, with potential applications spanning diagnostics to continuous computation inside living cells. In ctRSD circuits, RNA...
6.
Romantseva E, Alperovich N, Ross D, Lund S, Strychalski E
Synth Biol (Oxf)
. 2022 Sep;
7(1):ysac015.
PMID: 36046152
DNA templates for protein production remain an unexplored source of variability in the performance of cell-free expression (CFE) systems. To characterize this variability, we investigated the effects of two common...
7.
Pelletier J, Glass J, Strychalski E
Trends Cell Biol
. 2022 Jul;
32(11):900-907.
PMID: 35907702
Genomically minimal cells, such as JCVI-syn3.0 and JCVI-syn3A, offer an empowering framework to study relationships between genotype and phenotype. With a polygenic basis, the fundamental physiological process of cell division...
8.
Schaffter S, Strychalski E
Sci Adv
. 2022 Mar;
8(12):eabl4354.
PMID: 35319994
Engineered molecular circuits that process information in biological systems could address emerging human health and biomanufacturing needs. However, such circuits can be difficult to rationally design and scale. DNA-based strand...
9.
Romantseva E, Tack D, Alperovich N, Ross D, Strychalski E
Methods Mol Biol
. 2022 Jan;
2433:3-50.
PMID: 34985735
Performance variability is a common challenge in cell-free protein production and hinders a wider adoption of these systems for both research and biomanufacturing. While the inherent stochasticity and complexity of...
10.
Tack D, Romantseva E, Tonner P, Pressman A, Rammohan J, Strychalski E
Curr Opin Syst Biol
. 2021 Oct;
23:32-37.
PMID: 34611570
Precise engineering of biological systems requires quantitative, high-throughput measurements, exemplified by progress in directed evolution. New approaches allow high-throughput measurements of phenotypes and their corresponding genotypes. When integrated into directed...