Elisabeth Scheer
Overview
Explore the profile of Elisabeth Scheer including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
772
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Recent Articles
1.
Harel T, Spicher C, Scheer E, Buchan J, Cech J, Folland C, et al.
Brain
. 2024 May;
147(8):2732-2744.
PMID: 38753057
Deubiquitination is crucial for the proper functioning of numerous biological pathways, such as DNA repair, cell cycle progression, transcription, signal transduction and autophagy. Accordingly, pathogenic variants in deubiquitinating enzymes (DUBs)...
2.
Yayli G, Bernardini A, Mendoza Sanchez P, Scheer E, Damilot M, Essabri K, et al.
Cell Rep
. 2023 Sep;
42(9):113099.
PMID: 37682711
To understand the function of multisubunit complexes, it is of key importance to uncover the precise mechanisms that guide their assembly. Nascent proteins can find and bind their interaction partners...
3.
Yayli G, Bernardini A, Mendoza Sanchez P, Scheer E, Damilot M, Essabri K, et al.
bioRxiv
. 2023 Aug;
PMID: 37577620
To understand the function of multisubunit complexes it is of key importance to uncover the precise mechanisms that guide their assembly. Nascent proteins can find and bind their interaction partners...
4.
Bernardini A, Mukherjee P, Scheer E, Kamenova I, Antonova S, Mendoza Sanchez P, et al.
Nat Struct Mol Biol
. 2023 Jun;
30(8):1141-1152.
PMID: 37386215
Large heteromeric multiprotein complexes play pivotal roles at every step of gene expression in eukaryotic cells. Among them, the 20-subunit basal transcription factor TFIID nucleates the RNA polymerase II preinitiation...
5.
Bernardini A, Mukherjee P, Scheer E, Kamenova I, Antonova S, Mendoza Sanchez P, et al.
bioRxiv
. 2023 Apr;
PMID: 37066372
Large heteromeric multiprotein complexes play pivotal roles at every step of gene expression in eukaryotic cells. Among them, the 20-subunit basal transcription factor TFIID nucleates RNA polymerase II preinitiation complex...
6.
Fischer V, Hisler V, Scheer E, Lata E, Morlet B, Plassard D, et al.
Nucleic Acids Res
. 2022 Jul;
50(14):7972-7990.
PMID: 35871303
Coactivator complexes regulate chromatin accessibility and transcription. SAGA (Spt-Ada-Gcn5 Acetyltransferase) is an evolutionary conserved coactivator complex. The core module scaffolds the entire SAGA complex and adopts a histone octamer-like structure,...
7.
Arede L, Foerner E, Wind S, Kulkarni R, Domingues A, Giotopoulos G, et al.
Blood Adv
. 2021 Oct;
6(1):165-180.
PMID: 34654054
Epigenetic histone modifiers are key regulators of cell fate decisions in normal and malignant hematopoiesis. Their enzymatic activities are of particular significance as putative therapeutic targets in leukemia. In contrast,...
8.
Scheer E, Luo J, Bernardini A, Ruffenach F, Garnier J, Kolb-Cheynel I, et al.
J Biol Chem
. 2021 Oct;
297(5):101288.
PMID: 34634302
The human general transcription factor TFIID is composed of the TATA-binding protein (TBP) and 13 TBP-associated factors (TAFs). In eukaryotic cells, TFIID is thought to nucleate RNA polymerase II (Pol...
9.
Antonova S, Haffke M, Corradini E, Mikuciunas M, Low T, Signor L, et al.
Nat Struct Mol Biol
. 2018 Dec;
25(12):1119-1127.
PMID: 30510221
TFIID is a cornerstone of eukaryotic gene regulation. Distinct TFIID complexes with unique subunit compositions exist and several TFIID subunits are shared with other complexes, thereby conveying precise cellular control...
10.
Gupta K, Watson A, Baptista T, Scheer E, Chambers A, Koehler C, et al.
Elife
. 2017 Nov;
6.
PMID: 29111974
General transcription factor TFIID is a key component of RNA polymerase II transcription initiation. Human TFIID is a megadalton-sized complex comprising TATA-binding protein (TBP) and 13 TBP-associated factors (TAFs). TBP...