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Elisabeth Le Rumeur

Explore the profile of Elisabeth Le Rumeur including associated specialties, affiliations and a list of published articles. Areas
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Articles 37
Citations 597
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Recent Articles
1.
Mias-Lucquin D, Dos Santos Morais R, Cheron A, Lagarrigue M, Winder S, Chenuel T, et al.
J Struct Biol . 2019 Nov; 209(1):107411. PMID: 31689503
Dystrophin is a large intracellular protein that prevents sarcolemmal ruptures by providing a mechanical link between the intracellular actin cytoskeleton and the transmembrane dystroglycan complex. Dystrophin deficiency leads to the...
2.
Mias-Lucquin D, Cheron A, Le Rumeur E, Hubert J, Delalande O
Protein Sci . 2018 Nov; 28(3):561-570. PMID: 30468271
Coiled-coil domain is a structural motif found in proteins crucial for achievement of central biological processes, such as cellular cohesion or neuro-transmission. The coiled-coil fold consists of alpha-helices bundle that...
3.
Dos Santos Morais R, Delalande O, Perez J, Mias-Lucquin D, Lagarrigue M, Martel A, et al.
Biophys J . 2018 Sep; 115(7):1231-1239. PMID: 30197181
Scaffolding proteins play important roles in supporting the plasma membrane (sarcolemma) of muscle cells. Among them, dystrophin strengthens the sarcolemma through protein-lipid interactions, and its absence due to gene mutations...
4.
Delalande O, Molza A, Dos Santos Morais R, Cheron A, Pollet E, Raguenes-Nicol C, et al.
J Biol Chem . 2018 Mar; 293(18):6637-6646. PMID: 29535188
Dystrophin, encoded by the gene, is critical for maintaining plasma membrane integrity during muscle contraction events. Mutations in the gene disrupting the reading frame prevent dystrophin production and result in...
5.
Dos Santos Morais R, Delalande O, Perez J, Mouret L, Bondon A, Martel A, et al.
Langmuir . 2017 Jun; 33(26):6572-6580. PMID: 28581294
Obtaining structural information on integral or peripheral membrane proteins is currently arduous due to the difficulty of their solubilization, purification, and crystallization (for X-ray crystallography (XRC) application). To overcome this...
6.
Delalande O, Czogalla A, Hubert J, Sikorski A, Le Rumeur E
Subcell Biochem . 2017 Jan; 82:373-403. PMID: 28101868
Dystrophin and Spectrin are two proteins essential for the organization of the cytoskeleton and for the stabilization of membrane cells. The comparison of these two sister proteins, and with the...
7.
Ameziane-Le Hir S, Paboeuf G, Tascon C, Hubert J, Le Rumeur E, Vie V, et al.
Biochemistry . 2016 Jul; 55(29):4018-26. PMID: 27367833
Dystrophin (DYS) is a membrane skeleton protein whose mutations lead to lethal Duchenne muscular dystrophy or to the milder Becker muscular dystrophy (BMD). One third of BMD "in-frame" exon deletions...
8.
Oruc Z, Oblet C, Boumediene A, Druilhe A, Pascal V, Le Rumeur E, et al.
J Am Soc Nephrol . 2016 Jan; 27(9):2748-61. PMID: 26825533
IgA1 mesangial deposition is the hallmark of IgA nephropathy and Henoch-Schönlein purpura, the onset of which often follows infections. Deposited IgA has been reported as polymeric, J chain associated, and...
9.
Molza A, Mangat K, Le Rumeur E, Hubert J, Menhart N, Delalande O
J Biol Chem . 2015 Sep; 290(49):29531-41. PMID: 26378238
Duchenne muscular dystrophy is a lethal genetic defect that is associated with the absence of dystrophin protein. Lack of dystrophin protein completely abolishes muscular nitric-oxide synthase (NOS) function as a...
10.
Le Rumeur E
Bosn J Basic Med Sci . 2015 Aug; 15(3):14-20. PMID: 26295289
Mutations of the dystrophin DMD gene, essentially deletions of one or several exons, are the cause of two devastating and to date incurable diseases, Duchenne (DMD) and Becker (BMD) muscular...