Elisabeth Kastner
Overview
Explore the profile of Elisabeth Kastner including associated specialties, affiliations and a list of published articles.
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11
Citations
234
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Recent Articles
1.
Feather L, Nadella V, Kastner E, Perrie Y, Hilton A, Devitt A
Sci Rep
. 2022 Jul;
12(1):12448.
PMID: 35859154
Liposomes are a strong supporting tool in vaccine technology, as they are a versatile system that not only act as antigen delivery systems but also adjuvants that can be highly...
2.
Dimov N, Kastner E, Hussain M, Perrie Y, Szita N
Sci Rep
. 2018 Apr;
8(1):6762.
PMID: 29691461
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
3.
Dimov N, Kastner E, Hussain M, Perrie Y, Szita N
Sci Rep
. 2017 Sep;
7(1):12045.
PMID: 28935923
Liposomes are lipid based bilayer vesicles that can encapsulate, deliver and release low-soluble drugs and small molecules to a specific target site in the body. They are currently exploited in...
4.
Joshi S, Hussain M, Roces C, Anderluzzi G, Kastner E, Salmaso S, et al.
Int J Pharm
. 2016 Nov;
514(1):160-168.
PMID: 27863660
Despite the substantial body of research investigating the use of liposomes, niosomes and other bilayer vesicles for drug delivery, the translation of these systems into licensed products remains limited. Indeed,...
5.
Perrie Y, Kastner E, Khadke S, Roces C, Stone P
Methods Mol Biol
. 2016 Oct;
1494:127-144.
PMID: 27718190
A wide range of studies have shown that liposomes can act as suitable adjuvants for a range of vaccine antigens. Properties such as their amphiphilic character and biphasic nature allow...
6.
Roces C, Kastner E, Stone P, Lowry D, Perrie Y
Pharmaceutics
. 2016 Sep;
8(3).
PMID: 27649231
Quantification of the lipid content in liposomal adjuvants for subunit vaccine formulation is of extreme importance, since this concentration impacts both efficacy and stability. In this paper, we outline a...
7.
Perrie Y, Crofts F, Devitt A, Griffiths H, Kastner E, Nadella V
Adv Drug Deliv Rev
. 2015 Nov;
99(Pt A):85-96.
PMID: 26576719
Liposomes not only offer the ability to enhance drug delivery, but can effectively act as vaccine delivery systems and adjuvants. Their flexibility in size, charge, bilayer rigidity and composition allow...
8.
Kastner E, Verma V, Lowry D, Perrie Y
Int J Pharm
. 2015 Mar;
485(1-2):122-30.
PMID: 25725309
Besides their well-described use as delivery systems for water-soluble drugs, liposomes have the ability to act as a solubilizing agent for drugs with low aqueous solubility. However, a key limitation...
9.
Kastner E, Hussain M, Bramwell V, Christensen D, Perrie Y
J Pharm Pharmacol
. 2015 Feb;
67(3):450-63.
PMID: 25677402
Objective: In this study, we have used a chemometrics-based method to correlate key liposomal adjuvant attributes with in-vivo immune responses based on multivariate analysis. Methods: The liposomal adjuvant composed of...
10.
Kastner E, Kaur R, Lowry D, Moghaddam B, Wilkinson A, Perrie Y
Int J Pharm
. 2014 Dec;
477(1-2):361-8.
PMID: 25455778
Microfluidics has recently emerged as a new method of manufacturing liposomes, which allows for reproducible mixing in miliseconds on the nanoliter scale. Here we investigate microfluidics-based manufacturing of liposomes. The...