Elisabeth G Foerster
Overview
Explore the profile of Elisabeth G Foerster including associated specialties, affiliations and a list of published articles.
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9
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522
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Recent Articles
1.
Foerster E, Tsang D, Goyal S, Robertson S, Robert L, Maughan H, et al.
Mucosal Immunol
. 2023 Feb;
16(2):135-152.
PMID: 36792009
The breakdown of the intestinal mucosal barrier is thought to underlie the progression to Crohn disease (CD), whereby numerous risk factors contribute. For example, a genetic polymorphism of the autophagy...
2.
Tsang D, Wang R, De Sa O, Ayyaz A, Foerster E, Bayer G, et al.
Gut Microbes
. 2022 Aug;
14(1):2108281.
PMID: 35939622
The small intestinal epithelial barrier inputs signals from the gut microbiota in order to balance physiological inflammation and tolerance, and to promote homeostasis. Understanding the dynamic relationship between microbes and...
3.
Hezaveh K, Shinde R, Klotgen A, Halaby M, Lamorte S, Ciudad M, et al.
Immunity
. 2022 Feb;
55(2):324-340.e8.
PMID: 35139353
The aryl hydrocarbon receptor (AhR) is a sensor of products of tryptophan metabolism and a potent modulator of immunity. Here, we examined the impact of AhR in tumor-associated macrophage (TAM)...
4.
Foerster E, Mukherjee T, Cabral-Fernandes L, Rocha J, Girardin S, Philpott D
Autophagy
. 2021 Apr;
18(1):86-103.
PMID: 33906557
Macroautophagy/autophagy is a cellular catabolic process that results in lysosome-mediated recycling of organelles and protein aggregates, as well as the destruction of intracellular pathogens. Its role in the maintenance of...
5.
Maisonneuve C, Tsang D, Foerster E, Robert L, Mukherjee T, Prescott D, et al.
Cell Rep
. 2021 Jan;
34(4):108677.
PMID: 33503439
Pioneering studies from the early 1980s suggested that bacterial peptidoglycan-derived muramyl peptides (MPs) could exert either stimulatory or immunosuppressive functions depending, in part, on chronicity of exposure. However, this Janus-faced...
6.
Foerster E, Girardin S
Cell Host Microbe
. 2019 May;
25(5):632-634.
PMID: 31071290
In this issue of Cell Host & Microbe, Liang et al. (2019) show that α-defensins in the gastrointestinal tract sustain defenses to enteric pathogens during starvation. mTOR-dependent sensing of nutrient...
7.
Mukherjee T, Hovingh E, Foerster E, Abdel-Nour M, Philpott D, Girardin S
Arch Biochem Biophys
. 2018 Dec;
670:69-81.
PMID: 30578751
NOD1 and NOD2 are related intracellular sensors of bacterial peptidoglycan and belong to the Nod-like receptor (NLR) family of innate immune proteins that play fundamental and pleiotropic roles in host...
8.
Sorbara M, Foerster E, Tsalikis J, Abdel-Nour M, Mangiapane J, Sirluck-Schroeder I, et al.
Cell Host Microbe
. 2018 May;
23(5):644-652.e5.
PMID: 29746835
In physiological settings, the complement protein C3 is deposited on all bacteria, including invasive pathogens. However, because experimental host-bacteria systems typically use decomplemented serum to avoid the lytic action of...
9.
Tattoli I, Killackey S, Foerster E, Molinaro R, Maisonneuve C, Rahman M, et al.
Cell Rep
. 2016 Mar;
14(11):2576-86.
PMID: 26971996
The mitochondrial Nod-like receptor protein NLRX1 protects against colorectal tumorigenesis through mechanisms that remain unclear. Using mice with an intestinal epithelial cells (IEC)-specific deletion of Nlrx1, we find that NLRX1...