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Elisa Taiana

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Articles 39
Citations 691
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Recent Articles
1.
Puccio N, Manzotti G, Mereu E, Torricelli F, Ronchetti D, Cumerlato M, et al.
Haematologica . 2024 Jul; 109(12):4040-4055. PMID: 38988264
Multiple myeloma (MM) is a dreadful disease, marked by the uncontrolled proliferation of clonal plasma cells within the bone marrow. It is characterized by a highly heterogeneous clinical and molecular...
2.
Lazzaroni F, Matera A, Marella A, Maeda A, Castellano G, Marchetti A, et al.
Blood Adv . 2024 Jun; 8(15):3972-3984. PMID: 38830132
Smoldering multiple myeloma (SMM) is an asymptomatic plasma cell (PC) neoplasm that may evolve with variable frequency into multiple myeloma (MM). SMM is initiated by chromosomal translocations involving the immunoglobulin...
3.
Ronchetti D, Traini V, Silvestris I, Fabbiano G, Passamonti F, Bolli N, et al.
Cancer Gene Ther . 2024 Mar; 31(7):984-994. PMID: 38493226
NONO is a member of the Drosophila behavior/human splicing (DBHS) family of proteins. NONO is a multifunctional protein that acts as a "molecular scaffold" to carry out versatile biological activities...
4.
Bandini C, Mereu E, Paradzik T, Labrador M, Maccagno M, Cumerlato M, et al.
Exp Hematol Oncol . 2023 Aug; 12(1):71. PMID: 37563685
Background: Multiple myeloma (MM) is an incurable plasma cell malignancy, accounting for approximately 1% of all cancers. Despite recent advances in the treatment of MM, due to the introduction of...
5.
Favasuli V, Ronchetti D, Silvestris I, Puccio N, Fabbiano G, Traini V, et al.
Haematologica . 2023 Jul; 109(1):231-244. PMID: 37439377
DIS3 gene mutations occur in approximately 10% of patients with multiple myeloma (MM); furthermore, DIS3 expression can be affected by monosomy 13 and del(13q), found in roughly 40% of MM...
6.
Matera A, Marella A, Maeda A, Da Via M, Lazzaroni F, Fabris S, et al.
Int J Mol Sci . 2022 Dec; 23(24). PMID: 36555330
Multiple myeloma (MM) has a highly heterogeneous genetic background, which complicates its molecular tracking over time. Nevertheless, each MM patient's malignant plasma cells (PCs) share unique V(D)J rearranged sequences at...
7.
Ronchetti D, Favasuli V, Silvestris I, Todoerti K, Torricelli F, Bolli N, et al.
Discov Oncol . 2022 Nov; 13(1):124. PMID: 36367609
Purpose: The NONO protein belongs to the multifunctional family of proteins that can bind DNA, RNA and proteins. It is located in the nucleus of most mammalian cells and can...
8.
Taiana E, Bandini C, Favasuli V, Ronchetti D, Silvestris I, Puccio N, et al.
Haematologica . 2022 Sep; 108(1):219-233. PMID: 36073514
Long non-coding RNA NEAT1 is the core structural component of the nuclear paraspeckle (PS) organelles and it has been found to be deregulated in multiple myeloma (MM) patients. Experimental evidence...
9.
Laurenzi T, Palazzolo L, Taiana E, Saporiti S, Ben Mariem O, Guerrini U, et al.
Int J Mol Sci . 2022 Jul; 23(14). PMID: 35886974
NONO and SFPQ are involved in multiple nuclear processes (e.g., pre-mRNA splicing, DNA repair, and transcriptional regulation). These proteins, along with NEAT1, enable paraspeckle formation, thus promoting multiple myeloma cell...
10.
Todoerti K, Ronchetti D, Puccio N, Silvestris I, Favasuli V, Amodio N, et al.
Cancers (Basel) . 2021 Nov; 13(21). PMID: 34771679
The biological impact of long non-coding RNAs (lncRNAs) in multiple myeloma (MM) is becoming an essential aspect of the investigation, which may contribute to understanding the disease's complex pathobiology, providing...