Elisa Leimgruber
Overview
Explore the profile of Elisa Leimgruber including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
134
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Recent Articles
1.
Sarter K, Leimgruber E, Gobet F, Agrawal V, Dunand-Sauthier I, Barras E, et al.
J Exp Med
. 2016 Jan;
213(2):177-87.
PMID: 26809444
Evidence has recently emerged that butyrophilins, which are members of the extended B7 family of co-stimulatory molecules, have diverse functions in the immune system. We found that the human and...
2.
Falconnet D, She J, Tornay R, Leimgruber E, Bernasconi D, Lagopoulos L, et al.
Anal Chem
. 2015 Jan;
87(3):1582-9.
PMID: 25567587
We describe a multiplexing technology, named Evalution, based on novel digitally encoded microparticles in microfluidic channels. Quantitative multiplexing is becoming increasingly important for research and routine clinical diagnostics, but fast,...
3.
Seguin-Estevez Q, De Palma R, Krawczyk M, Leimgruber E, Villard J, Picard C, et al.
J Immunol
. 2009 Jul;
183(4):2545-53.
PMID: 19620312
Classical and nonclassical MHC class II (MHCII) genes are coregulated by the transcription factor RFX (regulatory factor X) and the transcriptional coactivator CIITA. RFX coordinates the assembly of a multiprotein...
4.
Nucleosome eviction from MHC class II promoters controls positioning of the transcription start site
Leimgruber E, Seguin-Estevez Q, Dunand-Sauthier I, Rybtsova N, Schmid C, Ambrosini G, et al.
Nucleic Acids Res
. 2009 Mar;
37(8):2514-28.
PMID: 19264803
Nucleosome depletion at transcription start sites (TSS) has been documented genome-wide in multiple eukaryotic organisms. However, the mechanisms that mediate this nucleosome depletion and its functional impact on transcription remain...
5.
Krawczyk M, Seguin-Estevez Q, Leimgruber E, Sperisen P, Schmid C, Bucher P, et al.
PLoS Genet
. 2008 Apr;
4(4):e1000058.
PMID: 18437201
The class II trans-activator CIITA is a transcriptional co-activator required for the expression of Major Histocompatibility Complex (MHC) genes. Although the latter function is well established, the global target-gene specificity...
6.
Masson P, Leimgruber E, Creton S, Collart M
Nucleic Acids Res
. 2007 Dec;
36(2):539-49.
PMID: 18048413
Negative co-factor 2 (NC2) is a conserved eukaryotic complex composed of two subunits, NC2alpha (Drap1) and NC2beta (Dr1) that associate through a histone-fold motif. In this work, we generated mutants...
7.
Rybtsova N, Leimgruber E, Seguin-Estevez Q, Dunand-Sauthier I, Krawczyk M, Reith W
Nucleic Acids Res
. 2007 May;
35(10):3431-41.
PMID: 17478518
Posttranslational histone modifications associated with actively expressed genes are generally believed to be introduced primarily by histone-modifying enzymes that are recruited by transcription factors or their associated co-activators. We have...
8.
Krawczyk M, Leimgruber E, Seguin-Estevez Q, Dunand-Sauthier I, Barras E, Reith W
Nucleic Acids Res
. 2006 Dec;
35(2):595-605.
PMID: 17175541
The small GTPase RAB4 regulates endocytic recycling, a process that contributes to Major Histocompatibility Complex (MHC)-mediated antigen presentation by specialized antigen presenting cells (APC) of the immune system. The gene...