Elina Hamalainen
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Explore the profile of Elina Hamalainen including associated specialties, affiliations and a list of published articles.
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15
Citations
93
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Recent Articles
1.
Heiskanen M, Banuelos I, Manninen E, Andrade P, Hamalainen E, Puhakka N, et al.
Epilepsia
. 2024 Oct;
65(12):3703-3716.
PMID: 39401067
Objective: This study was undertaken to test whether the postinjury plasma concentration of phosphorylated neurofilament heavy chain (pNF-H), a marker of axonal injury, is a prognostic biomarker for the development...
2.
Kyyriainen J, Andrade P, Ndode-Ekane X, Manninen E, Hamalainen E, Rauramaa T, et al.
Epilepsy Res
. 2024 Jan;
200:107301.
PMID: 38244466
Objective: To assess the prevalence of brain abscesses as a confounding factor for the diagnosis of post-traumatic epilepsy (PTE) in a rat model of lateral fluid-percussion-induced (FPI) traumatic brain injury...
3.
Ndode-Ekane X, Ali I, Santana-Gomez C, Casillas-Espinosa P, Andrade P, Smith G, et al.
Epilepsy Res
. 2023 Dec;
199:107263.
PMID: 38056191
Objective: Project 1 of the Preclinical Multicenter Epilepsy Bioinformatics Study for Antiepileptogenic Therapy (EpiBioS4Rx) consortium aims to identify preclinical biomarkers for antiepileptogenic therapies following traumatic brain injury (TBI). The international...
4.
Kajevu N, Lipponen A, Andrade P, Banuelos I, Puhakka N, Hamalainen E, et al.
Int J Mol Sci
. 2023 Sep;
24(18).
PMID: 37762352
We tested a hypothesis that in silico-discovered compounds targeting traumatic brain injury (TBI)-induced transcriptomics dysregulations will mitigate TBI-induced molecular pathology and augment the effect of co-administered antiseizure treatment, thereby alleviating...
5.
Kyyriainen J, Andrade P, Hamalainen E, Pitkanen A
Neurotrauma Rep
. 2023 Jun;
4(1):384-395.
PMID: 37350791
We report on a case study of a Wistar rat that was investigated in detail because it exhibited no N3 sleep in electroencephalography (EEG) after lateral fluid-percussion injury (FPI)-induced traumatic...
6.
Manninen E, Chary K, De Feo R, Hamalainen E, Andrade P, Paananen T, et al.
Biomedicines
. 2022 Nov;
10(11).
PMID: 36359242
It is necessary to develop reliable biomarkers for epileptogenesis and cognitive impairment after traumatic brain injury when searching for novel antiepileptogenic and cognition-enhancing treatments. We hypothesized that a multiparametric magnetic...
7.
Ndode-Ekane X, Immonen R, Hamalainen E, Manninen E, Andrade P, Ciszek R, et al.
Biomedicines
. 2022 Sep;
10(9).
PMID: 36140398
Brain atrophy induced by traumatic brain injury (TBI) progresses in parallel with epileptogenesis over time, and thus accurate placement of intracerebral electrodes to monitor seizure initiation and spread at the...
8.
De Feo R, Manninen E, Chary K, Hamalainen E, Immonen R, Andrade P, et al.
Epilepsia
. 2022 Apr;
63(7):1849-1861.
PMID: 35451496
Objective: This study was undertaken to identify prognostic biomarkers for posttraumatic epileptogenesis derived from parameters related to the hippocampal position and orientation. Methods: Data were derived from two preclinical magnetic...
9.
De Feo R, Hamalainen E, Manninen E, Immonen R, Valverde J, Ndode-Ekane X, et al.
Front Neurol
. 2022 Mar;
13:820267.
PMID: 35250823
Registration-based methods are commonly used in the automatic segmentation of magnetic resonance (MR) brain images. However, these methods are not robust to the presence of gross pathologies that can alter...
10.
Kyyriainen J, Kajevu N, Banuelos I, Lara L, Lipponen A, Balosso S, et al.
Int J Mol Sci
. 2021 Oct;
22(19).
PMID: 34638900
We assessed the effect of antioxidant therapy using the Food and Drug Administration-approved respiratory drug -acetylcysteine (NAC) or sulforaphane (SFN) as monotherapies or duotherapy in vitro in neuron-BV2 microglial co-cultures...