Eliana C Martinez
Overview
Explore the profile of Eliana C Martinez including associated specialties, affiliations and a list of published articles.
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32
Citations
610
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Recent Articles
1.
McLaughlin V, Alsumali A, Liu R, Klok R, Martinez E, Nourhussein I, et al.
Adv Ther
. 2023 Oct;
41(1):130-151.
PMID: 37851297
Introduction: Pulmonary arterial hypertension (PAH) is a rare, progressive disease associated with significant morbidity and mortality. The phase 3 STELLAR trial tested sotatercept plus background therapy (BGT) versus placebo plus...
2.
Yanucil C, Kentrup D, Li X, Grabner A, Schramm K, Martinez E, et al.
Sci Rep
. 2022 May;
12(1):7326.
PMID: 35513431
Fibroblast growth factor (FGF) 21, a hormone that increases insulin sensitivity, has shown promise as a therapeutic agent to improve metabolic dysregulation. Here we report that FGF21 directly targets cardiac...
3.
Martinez E, Li J, Arthur Ataam J, Tokarski K, Thakur H, Karakikes I, et al.
Gene Ther
. 2022 Feb;
30(7-8):543-551.
PMID: 35102273
Ischemic cardiomyopathy is a leading cause of death and an unmet clinical need. Adeno-associated virus (AAV) gene-based therapies hold great promise for treating and preventing heart failure. Previously we showed...
4.
Li J, Tan Y, Passariello C, Martinez E, Kritzer M, Li X, et al.
Circulation
. 2020 Sep;
142(22):2138-2154.
PMID: 32933333
Background: Concentric and eccentric cardiac hypertrophy are associated with pressure and volume overload, respectively, in cardiovascular disease both conferring an increased risk of heart failure. These contrasting forms of hypertrophy...
5.
Batlahally S, Franklin A, Damianos A, Huang J, Chen P, Sharma M, et al.
Sci Rep
. 2020 Jul;
10(1):12368.
PMID: 32704023
Preterm infants with bronchopulmonary dysplasia (BPD) and pulmonary hypertension (PH) have accelerated lung aging and poor long-term outcomes. Klotho is an antiaging protein that modulates oxidative stress, angiogenesis and fibrosis....
6.
Li X, Li J, Martinez E, Froese A, Passariello C, Henshaw K, et al.
Circulation
. 2020 Jul;
142(10):948-962.
PMID: 32611257
Background: The Ca/calmodulin-dependent phosphatase calcineurin is a key regulator of cardiac myocyte hypertrophy in disease. An unexplained paradox is how the β isoform of the calcineurin catalytic A-subunit (CaNAβ) is...
7.
Benny M, Hernandez D, Sharma M, Yousefi K, Kulandavelu S, Batlahally S, et al.
Physiol Rep
. 2020 Jan;
8(1):e14334.
PMID: 31925922
Supplemental oxygen (O ) therapy in preterm infants impairs lung development, but the impact of O on long-term systemic vascular structure and function has not been well-explored. The present study...
8.
de Carvalho L, Tan S, Ow G, Tang Z, Ching J, Kovalik J, et al.
JACC Basic Transl Sci
. 2018 Aug;
3(2):163-175.
PMID: 30062203
We identified a plasma signature of 11 C14 to C26 ceramides and 1 C16 dihydroceramide predictive of major adverse cardiovascular events in patients with acute myocardial infarction (AMI). Among patients...
9.
Martinez E, Lilyanna S, Wang P, Vardy L, Jiang X, Armugam A, et al.
J Mol Cell Cardiol
. 2017 Sep;
112:27-39.
PMID: 28865712
Rationale: Myocardial infarction (MI) triggers a dynamic microRNA response with the potential of yielding therapeutic targets. Objective: We aimed to identify novel aberrantly expressed cardiac microRNAs post-MI with potential roles...
10.
Passariello C, Martinez E, Thakur H, Cesareo M, Li J, Kapiloff M
J Mol Cell Cardiol
. 2016 Mar;
93:98-105.
PMID: 26940993
Noonan syndrome (NS) is a congenital disorder resulting from mutations of the Ras-Raf signaling pathway. Hypertrophic cardiomyopathy associated with RAF1 "RASopathy" mutations is a major risk factor for heart failure...