Elex S Harris
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Explore the profile of Elex S Harris including associated specialties, affiliations and a list of published articles.
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6
Citations
20
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Recent Articles
1.
Harris E, McIntire H, Mazur M, Schulz-Hildebrandt H, Leung H, Tearney G, et al.
Sci Rep
. 2024 Jul;
14(1):16568.
PMID: 39019950
Mucus stasis is a pathologic hallmark of muco-obstructive diseases, including cystic fibrosis (CF). Mucins, the principal component of mucus, are extensively modified with hydroxyl (O)-linked glycans, which are largely terminated...
2.
Harris E, McIntire H, Mazur M, Schulz-Hildebrandt H, Leung H, Tearney G, et al.
Res Sq
. 2024 Jun;
PMID: 38853971
Mucus stasis is a pathologic hallmark of muco-obstructive diseases, including cystic fibrosis (CF). Mucins, the principal component of mucus, are extensively modified with hydroxyl (O)-linked glycans, which are largely terminated...
3.
Donaldson S, Corcoran T, Pilewski J, Mogayzel P, Laube B, Boitet E, et al.
J Cyst Fibros
. 2023 Oct;
23(1):155-160.
PMID: 37845149
Background: The cystic fibrosis transmembrane conductance regulator (CFTR) modulator elexacaftor/tezacaftor/ivacaftor (E/T/I) is highly effective clinically for those with at least one F508del-CFTR allele. The effects of E/T/I on mucociliary clearance...
4.
Harris E, Novak L, Fernandez-Petty C, Lindgren N, Baker S, Birket S, et al.
J Cyst Fibros
. 2023 Sep;
22(6):1104-1112.
PMID: 37714777
Background: Mucus stasis, a hallmark of muco-obstructive disease, results from impaired mucociliary transport and leads to lung function decline and chronic infection. Although therapeutics that target mucus stasis in the...
5.
Easter M, Garth J, Harris E, Shei R, Helton E, Wei Y, et al.
Front Med (Lausanne)
. 2020 Aug;
7:317.
PMID: 32793609
Fibroblast growth factor receptor (FGFR) 4 has been shown to mediate pro-inflammatory signaling in the liver and airway epithelium in chronic obstructive pulmonary disease. In past reports, FGFR4 knockout (...
6.
Stanford D, Kim H, Bodduluri S, Lafontaine J, Byzek S, Schoeb T, et al.
Am J Physiol Lung Cell Mol Physiol
. 2020 May;
319(1):L11-L20.
PMID: 32374671
Structural changes to airway morphology, such as increased bronchial wall thickness (BWT) and airway wall area, are cardinal features of chronic obstructive pulmonary disease (COPD). Ferrets are a recently established...