Eleonora Palma
Overview
Explore the profile of Eleonora Palma including associated specialties, affiliations and a list of published articles.
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Articles
60
Citations
1031
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Recent Articles
1.
Puhakka N, Cifelli P, Ruffolo G, Gaeta A, Roseti C, Di Iacovo A, et al.
Exp Neurol
. 2025 Feb;
387:115183.
PMID: 39938858
Traumatic brain injury (TBI) is one of the leading causes of structural epilepsy. Our objective was to investigate the molecular and functional dysregulation of GABAergic neurotransmission during a wide time...
2.
Ghosh A, Ribeiro-Rodrigues L, Ruffolo G, Alfano V, Domingos C, Rei N, et al.
Br J Pharmacol
. 2024 Sep;
181(24):5041-5061.
PMID: 39300608
Background And Purpose: Adenosine, through the A receptor (AR), is an endogenous anticonvulsant. The development of adenosine receptor agonists as antiseizure medications has been hampered by their cardiac side effects....
3.
Scheper M, Sorensen F, Ruffolo G, Gaeta A, Lissner L, Anink J, et al.
Acta Neuropathol
. 2024 May;
147(1):80.
PMID: 38714540
GABAergic interneurons play a critical role in maintaining neural circuit balance, excitation-inhibition regulation, and cognitive function modulation. In tuberous sclerosis complex (TSC), GABAergic neuron dysfunction contributes to disrupted network activity...
4.
Gaeta A, Lissner L, Alfano V, Cifelli P, Morano A, Roseti C, et al.
Membranes (Basel)
. 2024 Mar;
14(3).
PMID: 38535283
Among the most prevalent neurological disorders, epilepsy affects about 1% of the population worldwide. We previously found, using human epileptic tissues, that GABAergic neurotransmission impairment is a key mechanism that...
5.
Sciaccaluga M, Ruffolo G, Palma E, Costa C
Curr Neuropharmacol
. 2023 May;
21(8):1736-1754.
PMID: 37143270
Despite the wide range of compounds currently available to treat epilepsy, there is still no drug that directly tackles the physiopathological mechanisms underlying its development. Indeed, antiseizure medications attempt to...
6.
Margotta C, Fabbrizio P, Ceccanti M, Cambieri C, Rufolo G, DAgostino J, et al.
Inflamm Regen
. 2023 Apr;
43(1):25.
PMID: 37072876
No abstract available.
7.
Margotta C, Fabbrizio P, Ceccanti M, Cambieri C, Ruffolo G, DAgostino J, et al.
Inflamm Regen
. 2023 Mar;
43(1):19.
PMID: 36895050
Background: Amyotrophic lateral sclerosis (ALS) is a heterogeneous disease in terms of onset and progression rate. This may account for therapeutic clinical trial failure. Transgenic SOD1G93A mice on C57 or...
8.
Tramutola A, Lanzillotta S, Aceto G, Pagnotta S, Ruffolo G, Cifelli P, et al.
Antioxidants (Basel)
. 2023 Jan;
12(1).
PMID: 36670973
Down syndrome (DS) is the most frequent genetic cause of intellectual disability and is strongly associated with Alzheimer's disease (AD). Brain insulin resistance greatly contributes to AD development in the...
9.
Ruffolo G, Gaeta A, Cannata B, Pinzaglia C, Aronica E, Morano A, et al.
Life (Basel)
. 2022 Dec;
12(12).
PMID: 36556407
Recently, the potential use of phytocannabinoids (pCBs) to treat different pathological conditions has attracted great attention in the scientific community. Among the different pCBs, cannabidiol (CBD) has showed interesting biological...
10.
Ruffolo G, Alfano V, Romagnolo A, Zimmer T, Mills J, Cifelli P, et al.
Sci Rep
. 2022 Oct;
12(1):17956.
PMID: 36289354
Gangliogliomas (GGs) are low-grade brain tumours that cause intractable focal epilepsy in children and adults. In GG, as in epileptogenic focal malformations (i.e., tuberous sclerosis complex, TSC), there is evidence...