Eleni Ritou
Overview
Explore the profile of Eleni Ritou including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
269
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Recent Articles
1.
Ritou E, Satta S, Petcherski A, Daskou M, Sharma M, Vasilopoulos H, et al.
Metabolism
. 2023 Feb;
141:155395.
PMID: 36842771
Background: Mitochondria regulate immune and organ function. It is unknown whether higher intracellular drug levels observed in peripheral blood mononuclear cells (PBMCs) treated with tenofovir alafenamide (TAF) compared to tenofovir...
2.
Petcherski A, Sharma M, Satta S, Daskou M, Vasilopoulos H, Hugo C, et al.
bioRxiv
. 2022 Mar;
PMID: 35233569
One-sentence Summary: Mitoquinone/mitoquinol mesylate has potent antiviral and anti-inflammatory activity in preclinical models of SARS-CoV-2 infection.
3.
Daskou M, Mu W, Sharma M, Vasilopoulos H, Heymans R, Ritou E, et al.
PLoS Pathog
. 2022 Jan;
18(1):e1010160.
PMID: 34995311
Novel therapeutic strategies are needed to attenuate increased systemic and gut inflammation that contribute to morbidity and mortality in chronic HIV infection despite potent antiretroviral therapy (ART). The goal of...
4.
Shen N, Korm S, Karantanos T, Li D, Zhang X, Ritou E, et al.
Commun Biol
. 2021 Nov;
4(1):1289.
PMID: 34785772
Triple-negative breast cancer (TNBC) is traditionally considered a glycolytic tumor with a poor prognosis while lacking targeted therapies. Here we show that high expression of dihydrolipoamide S-succinyltransferase (DLST), a tricarboxylic...
5.
Kelesidis T, Madhav S, Petcherski A, Cristelle H, OConnor E, Hultgren N, et al.
Virulence
. 2021 Sep;
12(1):2214-2227.
PMID: 34494942
An oral antiviral against SARS-CoV-2 that also attenuates inflammatory instigators of severe COVID-19 is not available to date. Herein, we show that the apoA-I mimetic peptide 4 F inhibits Spike...
6.
Mu W, Sharma M, Heymans R, Ritou E, Rezek V, Hamid P, et al.
AIDS
. 2020 Dec;
35(4):543-553.
PMID: 33306550
Objectives: Despite antiretroviral therapy (ART), there is an unmet need for therapies to mitigate immune activation in HIV infection. The goal of this study is to determine whether the apoA-I...
7.
Taddeo E, Alsabeeh N, Baghdasarian S, Wikstrom J, Ritou E, Sereda S, et al.
Diabetes
. 2019 Nov;
69(2):131-145.
PMID: 31740442
Fasting hyperinsulinemia precedes the development of type 2 diabetes. However, it is unclear whether fasting insulin hypersecretion is a primary driver of insulin resistance or a consequence of the progressive...
8.
Montemurro C, Nomoto H, Pei L, Parekh V, Vongbunyong K, Vadrevu S, et al.
Nat Commun
. 2019 Aug;
10(1):3507.
PMID: 31366929
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
9.
Montemurro C, Nomoto H, Pei L, Parekh V, Vongbunyong K, Vadrevu S, et al.
Nat Commun
. 2019 Jun;
10(1):2679.
PMID: 31213603
The islet in type 2 diabetes (T2D) is characterized by amyloid deposits derived from islet amyloid polypeptide (IAPP), a protein co-expressed with insulin by β-cells. In common with amyloidogenic proteins...
10.
Taddeo E, Stiles L, Sereda S, Ritou E, Wolf D, Abdullah M, et al.
Mol Metab
. 2018 Aug;
16:150-159.
PMID: 30098928
Objective: Islets from the same pancreas show remarkable variability in glucose sensitivity. While mitochondrial respiration is essential for glucose-stimulated insulin secretion, little is known regarding heterogeneity in mitochondrial function at...