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Elena Makareeva

Explore the profile of Elena Makareeva including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 2438
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Recent Articles
1.
Roth D, Pina J, Raju R, Iben J, Faucz F, Makareeva E, et al.
bioRxiv . 2024 May; PMID: 38798531
Orthodontic maxillary expansion relies on intrinsic mid-palatal suture mechanobiology to induce guided osteogenesis, yet establishment of the mid-palatal suture within the continuous secondary palate and causes of maxillary insufficiency remain...
2.
Makareeva E, Sousa M, Kent T, de Castro L, Collins M, Leikin S
J Bone Miner Res . 2024 Mar; 39(2):177-189. PMID: 38477760
Bone histomorphometry is a well-established approach to assessing skeletal pathology, providing a standard evaluation of the cellular components, architecture, mineralization, and growth of bone tissue. However, it depends in part...
3.
Mertz E, Makareeva E, Mirigian L, Leikin S
JBMR Plus . 2023 Jan; 7(1):e10701. PMID: 36699640
Relevance of mineralized nodules in two-dimensional (2D) osteoblast/osteocyte cultures to bone biology, pathology, and engineering is a decades old question, but a comprehensive answer appears to be still wanting. Bone-like...
4.
Gorrell L, Makareeva E, Omari S, Otsuru S, Leikin S
Adv Sci (Weinh) . 2022 Aug; 9(29):e2201273. PMID: 35988140
Cellular response to protein misfolding underlies multiple diseases. Collagens are the most abundant vertebrate proteins, yet little is known about cellular response to misfolding of their procollagen precursors. Osteoblasts (OBs)-the...
5.
Gorrell L, Omari S, Makareeva E, Leikin S
Cell Mol Life Sci . 2021 Nov; 78(24):8283-8300. PMID: 34779895
Secretion and quality control of large extracellular matrix proteins remain poorly understood and debated, particularly transport intermediates delivering folded proteins from the ER to Golgi and misfolded ones to lysosomes....
6.
Klionsky D, Abdel-Aziz A, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al.
Autophagy . 2021 Feb; 17(1):1-382. PMID: 33634751
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our...
7.
Omari S, Makareeva E, Gorrell L, Jarnik M, Lippincott-Schwartz J, Leikin S
Matrix Biol . 2020 Jun; 93:79-94. PMID: 32562852
Efficient quality control and export of procollagen from the cell is crucial for extracellular matrix homeostasis, yet it is still incompletely understood. One of the debated questions is the role...
8.
Cabral W, Fratzl-Zelman N, Weis M, Perosky J, Alimasa A, Harris R, et al.
Matrix Biol . 2020 Mar; 90:20-39. PMID: 32112888
Null mutations in CRTAP or P3H1, encoding cartilage-associated protein and prolyl 3-hydroxylase 1, cause the severe bone dysplasias, types VII and VIII osteogenesis imperfecta. Lack of either protein prevents formation...
9.
Omari S, Makareeva E, Roberts-Pilgrim A, Mirigian L, Jarnik M, Ott C, et al.
Proc Natl Acad Sci U S A . 2018 Oct; 115(43):E10099-E10108. PMID: 30287488
Type I collagen is the main component of bone matrix and other connective tissues. Rerouting of its procollagen precursor to a degradative pathway is crucial for osteoblast survival in pathologies...
10.
Makareeva E, Sun G, Mirigian L, Mertz E, Vera J, Espinoza N, et al.
PLoS One . 2018 Jul; 13(7):e0200264. PMID: 29990383
OI is a clinically and genetically heterogeneous disorder characterized by bone fragility. More than 90% of patients are heterozygous for mutations in type I collagen genes, COL1A1 and COL1A2, and...