Elena Magnani
Overview
Explore the profile of Elena Magnani including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
414
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0
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Recent Articles
1.
Magnani E, Macchi F, Randic T, Chen C, Madakashira B, Ranjan S, et al.
bioRxiv
. 2025 Jan;
PMID: 39763773
Tumor heterogeneity is the substrate for tumor evolution and the linchpin of treatment resistance. Cancer cell heterogeneity is largely attributed to distinct genetic changes within each cell population. However, the...
2.
Madakashira B, Magnani E, Ranjan S, Sadler K
Nucleic Acids Res
. 2024 Feb;
52(6):3069-3087.
PMID: 38321933
Coordinating epigenomic inheritance and cell cycle progression is essential for organogenesis. UHRF1 connects these functions during development by facilitating maintenance of DNA methylation and cell cycle progression. Here, we provide...
3.
Magnani E, Ramdas Nair A, McBain I, Delaney P, Chu J, Sadler K
Methods Mol Biol
. 2023 Sep;
2707:43-69.
PMID: 37668904
Liver disease affects millions of people worldwide, and the high morbidity and mortality is attributed in part to the paucity of treatment options. In many cases, liver injury self-resolves due...
4.
Pieralli F, Pomero F, Dentali F, Norbiato C, Attardo T, Vicari S, et al.
BMC Infect Dis
. 2023 Jul;
23(1):454.
PMID: 37422621
Background: Remdesivir is widely used for treatment of SARS-CoV-2 pneumonia. The aim of this study was to evaluate the characteristics of patients with moderate-to-severe COVID-19 treated with remdesivir, and their...
5.
Ajouaou Y, Magnani E, Madakashira B, Jenkins E, Sadler K
Cancers (Basel)
. 2023 May;
15(8).
PMID: 37190230
The ataxia-telangiectasia mutated () gene is activated in response to genotoxic stress and leads to activation of the tumor suppressor gene which induces either senescence or apoptosis as tumor suppressive...
6.
Tortola D, Magnani E, Giorgini E, Zani M, Pazzaglini C, Sambo P, et al.
SN Compr Clin Med
. 2022 Nov;
4(1):233.
PMID: 36320815
The impact of COVID-19 pandemic put the Italian health system into a test. In the period between September 2020 and June 2021, a weekly average of 114 SARS-CoV-2 infections were...
7.
Madakashira B, Zhang C, Macchi F, Magnani E, Sadler K
Genes (Basel)
. 2021 Aug;
12(7).
PMID: 34356097
Acquisition of cellular fate during development is initiated and maintained by well-coordinated patterns of gene expression that are dictated by the epigenetic landscape and genome organization in the nucleus. While...
8.
Zhang C, Macchi F, Magnani E, Sadler K
Nat Commun
. 2021 Jul;
12(1):4110.
PMID: 34226551
We hypothesized that the highly controlled pattern of gene expression that is essential for liver regeneration is encoded by an epigenetic code set in quiescent hepatocytes. Here we report that...
9.
Mancini M, Magnani E, Macchi F, Bonapace I
Nucleic Acids Res
. 2021 May;
49(11):6053-6068.
PMID: 33939809
During S phase, the cooperation between the macromolecular complexes regulating DNA synthesis, epigenetic information maintenance and DNA repair is advantageous for cells, as they can rapidly detect DNA damage and...
10.
Magnani E, Macchi F, Madakashira B, Zhang C, Alaydaroos F, Sadler K
Front Immunol
. 2021 Apr;
12:627926.
PMID: 33854502
Activation of transposable elements (TEs) can cause cellular damage. Cytoplasmic nucleic acid sensing pathways evolved to detect pathogens, but can also serve to cull cells with inappropriate TE activation as...