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Elena M Sorokina

Explore the profile of Elena M Sorokina including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 727
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Recent Articles
1.
Bond C, Hugelier S, Xing J, Sorokina E, Lakadamyali M
J Cell Biol . 2024 Nov; 224(1). PMID: 39485275
Late endosomes/lysosomes (LELs) are crucial for numerous physiological processes and their dysfunction is linked to many diseases. Proteomic analyses have identified hundreds of LEL proteins; however, whether these proteins are...
2.
Roozbahani G, Colosi P, Oravecz A, Sorokina E, Pfeifer W, Shokri S, et al.
Sci Adv . 2024 Jul; 10(27):eadn9423. PMID: 38968349
DNA origami nanostructures (DOs) are promising tools for applications including drug delivery, biosensing, detecting biomolecules, and probing chromatin substructures. Targeting these nanodevices to mammalian cell nuclei could provide impactful approaches...
3.
Bond C, Hugelier S, Xing J, Sorokina E, Lakadamyali M
bioRxiv . 2024 Apr; PMID: 38562776
Summary: This study develops a multiplexed and quantitative DNA-PAINT super-resolution imaging pipeline to investigate the distribution of late endosomal/lysosomal (LEL) proteins across individual LELs, revealing cell-type specific LEL sub-populations with...
4.
Roozbahani G, Colosi P, Oravecz A, Sorokina E, Pfeifer W, Shokri S, et al.
bioRxiv . 2024 Jan; PMID: 38260628
DNA origami (DO) are promising tools for or applications including drug delivery; biosensing, detecting biomolecules; and probing chromatin sub-structures. Targeting these nanodevices to mammalian cell nuclei could provide impactful approaches...
5.
Gyparaki M, Arab A, Sorokina E, Santiago-Ruiz A, Bohrer C, Xiao J, et al.
Proc Natl Acad Sci U S A . 2021 May; 118(19). PMID: 33952699
Tau is a microtubule-associated protein, which promotes neuronal microtubule assembly and stability. Accumulation of tau into insoluble aggregates known as neurofibrillary tangles (NFTs) is a pathological hallmark of several neurodegenerative...
6.
Vazquez-Medina J, Tao J, Patel P, Bannitz-Fernandes R, Dodia C, Sorokina E, et al.
Am J Physiol Lung Cell Mol Physiol . 2019 Feb; 316(4):L656-L668. PMID: 30702344
Peroxiredoxin 6 (Prdx6) is a multifunctional enzyme that serves important antioxidant roles by scavenging hydroperoxides and reducing peroxidized cell membranes. Prdx6 also plays a key role in cell signaling by...
7.
Mohan N, Sorokina E, Verdeny I, Alvarez A, Lakadamyali M
J Cell Biol . 2018 Dec; 218(2):632-643. PMID: 30567713
Microtubule post-translational modifications impart functional diversity to microtubules by affecting their dynamics, organization, and interaction with proteins. Using super-resolution microscopy, we show that only a small subpopulation of microtubules are...
8.
Fisher A, Vasquez-Medina J, Dodia C, Sorokina E, Tao J, Feinstein S
Redox Biol . 2017 Sep; 14:41-46. PMID: 28865296
Although lipid peroxidation associated with oxidative stress can result in cellular death, sub-lethal lipid peroxidation can gradually resolve with return to the pre-exposure state. We have shown that resolution of...
9.
Sorokina E, Dodia C, Zhou S, Tao J, Gao L, Raabe T, et al.
J Biol Chem . 2016 Feb; 291(17):9268-80. PMID: 26921317
Peroxiredoxin 6 (Prdx6), a bifunctional protein with phospholipase A2 (aiPLA2) and GSH peroxidase activities, protects lungs from oxidative stress and participates in lung surfactant phospholipid turnover. Prdx6 has been localized...
10.
Zhou S, Sorokina E, Harper S, Li H, Ralat L, Dodia C, et al.
Free Radic Biol Med . 2016 Feb; 94:145-56. PMID: 26891882
Peroxiredoxin 6 (Prdx6) is a unique 1-Cys member of the peroxiredoxin family with both GSH peroxidase and phospholipase A2 (PLA2) activities. It is highly expressed in the lung where it...