Elena Lopez-Jimenez
Overview
Explore the profile of Elena Lopez-Jimenez including associated specialties, affiliations and a list of published articles.
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17
Citations
624
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Recent Articles
1.
Wang D, Hadad N, Moss S, Lopez-Jimenez E, Johnson S, Maher T, et al.
bioRxiv
. 2024 Jun;
PMID: 38853935
Methods: We adopted three complementary approaches to explore the role of mLOY in the pathogenesis of PF. We used copy number on chromosome Y to estimate mLOY comparing patients in...
2.
A bile-based microRNA signature for differentiating malignant from benign pancreaticobiliary disease
Mato Prado M, Puik J, Castellano L, Lopez-Jimenez E, Liu D, Meijer L, et al.
Exp Hematol Oncol
. 2023 Dec;
12(1):101.
PMID: 38041102
Differentiating between pancreatic ductal adenocarcinoma (PDAC) and cholangiocarcinoma (CCA) is crucial for the appropriate course of treatment, especially with advancements in the role of neoadjuvant chemotherapies for PDAC, compared to...
3.
Tiana M, Lopez-Jimenez E, de Aja J, Barral A, Victorino J, Badia-Careaga C, et al.
Sci Adv
. 2022 Jul;
8(28):eabo3583.
PMID: 35857513
Pluripotent cells are a transient population of the mammalian embryo dependent on transcription factors, such as OCT4 and NANOG, which maintain pluripotency while suppressing lineage specification. However, these factors are...
4.
Lopez-Jimenez E, Gonzalez-Aguilera C
Genes (Basel)
. 2022 Jun;
13(6).
PMID: 35741764
Chromatin organization is essential to maintain a correct regulation of gene expression and establish cell identity. However, during cell division, the replication of the genetic material produces a global disorganization...
5.
Saavedra-Garcia P, Roman-Trufero M, Al-Sadah H, Blighe K, Lopez-Jimenez E, Christoforou M, et al.
Proc Natl Acad Sci U S A
. 2021 Apr;
118(17).
PMID: 33883278
Cancer cells can survive chemotherapy-induced stress, but how they recover from it is not known. Using a temporal multiomics approach, we delineate the global mechanisms of proteotoxic stress resolution in...
6.
Lopez-Jimenez E, Andres-Leon E
Noncoding RNA
. 2021 Mar;
7(1).
PMID: 33668203
The mammalian genome comprehends a small minority of genes that encode for proteins (barely 2% of the total genome in humans) and an immense majority of genes that are transcribed...
7.
von Arx C, Capozzi M, Lopez-Jimenez E, Ottaiano A, Tatangelo F, Di Mauro A, et al.
J Clin Med
. 2019 Aug;
8(9).
PMID: 31443481
Neuroendocrine neoplasms (NENs) comprise a heterogeneous group of rare malignancies, mainly originating from hormone-secreting cells, which are widespread in human tissues. The identification of mutations in ATRX/DAXX genes in sporadic...
8.
Lopez-Jimenez E, Rojas A, Andres-Leon E
Adv Exp Med Biol
. 2018 Sep;
1087:17-33.
PMID: 30259354
Circular RNAs (circRNAs) are noncoding and single-stranded RNA transcripts able to form covalently circular-closed structures. They are generated through alternative splicing events and widely expressed from human to viruses. CircRNAs...
9.
Glypican-1 is enriched in circulating-exosomes in pancreatic cancer and correlates with tumor burden
Frampton A, Mato Prado M, Lopez-Jimenez E, Fajardo-Puerta A, Jawad Z, Lawton P, et al.
Oncotarget
. 2018 May;
9(27):19006-19013.
PMID: 29721179
Background: Glypican-1 (GPC1) is expressed in pancreatic ductal adenocarcinoma (PDAC) cells and adjacent stromal fibroblasts. Recently, GPC1 circulating exosomes (crExos) have been shown to be able to detect early stages...
10.
Aguirre L, Alonso M, Badia-Careaga C, Rollan I, Arias C, Fernandez-Minan A, et al.
BMC Biol
. 2015 Apr;
13:26.
PMID: 25888893
Background: Recent genome-wide association studies have uncovered genomic loci that underlie an increased risk for atrial fibrillation, the major cardiac arrhythmia in humans. The most significant locus is located in...