Elena Khazina
Overview
Explore the profile of Elena Khazina including associated specialties, affiliations and a list of published articles.
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6
Citations
256
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0
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Recent Articles
1.
Chen Y, Khazina E, Izaurralde E, Weichenrieder O
Nucleic Acids Res
. 2021 May;
49(11):6489-6510.
PMID: 34038562
The CCR4 and CAF1 deadenylases physically interact to form the CCR4-CAF1 complex and function as the catalytic core of the larger CCR4-NOT complex. Together, they are responsible for the eventual...
2.
Khazina E, Weichenrieder O
Elife
. 2018 Mar;
7.
PMID: 29565245
LINE-1 (L1) is an autonomous retrotransposon, which acted throughout mammalian evolution and keeps contributing to human genotypic diversity, genetic disease and cancer. L1 encodes two essential proteins: L1ORF1p, a unique...
3.
MacLennan M, Garcia-Canadas M, Reichmann J, Khazina E, Wagner G, Playfoot C, et al.
Elife
. 2017 Aug;
6.
PMID: 28806172
Mobilization of retrotransposons to new genomic locations is a significant driver of mammalian genome evolution, but these mutagenic events can also cause genetic disorders. In humans, retrotransposon mobilization is mediated...
4.
Schneider A, Schmidt S, Jonas S, Vollmer B, Khazina E, Weichenrieder O
Nucleic Acids Res
. 2013 Sep;
41(22):10563-72.
PMID: 24003030
Non-LTR retrotransposons are mobile genetic elements and play a major role in eukaryotic genome evolution and disease. Similar to retroviruses they encode a reverse transcriptase, but their genomic integration mechanism...
5.
Khazina E, Truffault V, Buttner R, Schmidt S, Coles M, Weichenrieder O
Nat Struct Mol Biol
. 2011 Aug;
18(9):1006-14.
PMID: 21822284
The LINE-1 (L1) retrotransposon emerges as a major source of human interindividual genetic variation, with important implications for evolution and disease. L1 retrotransposition is poorly understood at the molecular level,...
6.
Khazina E, Weichenrieder O
Proc Natl Acad Sci U S A
. 2009 Jan;
106(3):731-6.
PMID: 19139409
Non-LTR retrotransposons (NLRs) are a unique class of mobile genetic elements that have significant impact on the evolution of eukaryotic genomes. However, the molecular details and functions of their encoded...