Elan Eisenmesser
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Explore the profile of Elan Eisenmesser including associated specialties, affiliations and a list of published articles.
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64
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Recent Articles
1.
Airway interfere with and infection and express secreted factors selectively targeting each pathogen
Tamkin E, Lorenz B, McCarty A, Fulte S, Eisenmesser E, Horswill A, et al.
Infect Immun
. 2024 Dec;
93(2):e0044524.
PMID: 39705185
The composition of the respiratory tract microbiome is a notable predictor of infection-related morbidities and mortalities among both adults and children. Species of which are largely present as commensals in...
2.
Lee E, Saviola A, Bevers S, Redzic J, Maroney S, Shaw S, et al.
Protein Sci
. 2024 Dec;
34(1):e5253.
PMID: 39660954
Streptococcus pneumoniae (S. pneumoniae) employs various metabolic pathways to generate nicotinamide adenine dinucleotide phosphate (NADPH), which is essential for redox balance, fatty acid synthesis, and energy production. GAPN, a non-phosphorylating...
3.
Fulte S, Atto B, McCarty A, Horn K, Redzic J, Eisenmesser E, et al.
mSphere
. 2024 Feb;
9(3):e0000624.
PMID: 38380941
Importance: The microbiome provides a critical layer of protection against infection with bacterial pathogens. This protection is accomplished through a variety of mechanisms, including interference with pathogen growth and adherence...
4.
Klontz E, Obi J, Wang Y, Glendening G, Carr J, Tsibouris C, et al.
J Biol Chem
. 2023 Sep;
299(11):105290.
PMID: 37758001
Toll-like and interleukin-1/18 receptor/resistance (TIR) domain-containing proteins function as important signaling and immune regulatory molecules. TIR domain-containing proteins identified in eukaryotic and prokaryotic species also exhibit NAD+ hydrolase activity in...
5.
Lee E, Redzic J, Saviola A, Li X, Ebmeier C, Kutateladze T, et al.
Protein Sci
. 2023 Feb;
32(4):e4603.
PMID: 36807437
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) nucleocapsid protein is the most abundantly expressed viral protein during infection where it targets both RNA and host proteins. However, identifying how a...
6.
Redzic J, Rahkola J, Tran N, Holyoak T, Lee E, Martin-Galiano A, et al.
Commun Biol
. 2022 Nov;
5(1):1190.
PMID: 36336763
The mucosal adaptive immune response is dependent on the production of IgA antibodies and particularly IgA1, yet opportunistic bacteria have evolved mechanisms to specifically block this response by producing IgA1...
7.
Schultz J, McCarthy M, Rester C, Sabourin K, Annen K, DomBourian M, et al.
J Clin Microbiol
. 2021 Apr;
59(6).
PMID: 33795412
Serological testing of large representative populations for antibodies to SARS-CoV-2 is needed to estimate seroprevalence, transmission dynamics, and the duration of antibody responses from natural infection and vaccination. In this...
8.
Wang Z, Rahkola J, Redzic J, Chi Y, Tran N, Holyoak T, et al.
Nat Commun
. 2020 Nov;
11(1):6063.
PMID: 33247098
Opportunistic pathogens such as Streptococcus pneumoniae secrete a giant metalloprotease virulence factor responsible for cleaving host IgA1, yet the molecular mechanism has remained unknown since their discovery nearly 30 years...
9.
de Graaf D, Maas R, Smeekens S, Eisenmesser E, Redzic J, Helsen M, et al.
Cytokine
. 2020 Oct;
137:155334.
PMID: 33128926
Interleukin (IL)-38 belongs to the IL-1 family and is part of the IL-36 subfamily due to its binding to the IL-36 Receptor (IL-1R6). In the current study, we assessed the...
10.
Bahmed K, Henry C, Holliday M, Redzic J, Ciobanu M, Zhang F, et al.
Cancer Cell Int
. 2012 May;
12(1):19.
PMID: 22631225
Background: Although the peptidyl-prolyl isomerase, cyclophilin-A (peptidyl-prolyl isomerase, PPIA), has been studied for decades in the context of its intracellular functions, its extracellular roles as a major contributor to both...