Ekaterina Pchitskaya
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Explore the profile of Ekaterina Pchitskaya including associated specialties, affiliations and a list of published articles.
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18
Citations
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Recent Articles
11.
Pchitskaya E, Bezprozvanny I
Front Synaptic Neurosci
. 2020 Oct;
12:31.
PMID: 33117142
Dendritic spines are small protrusions from the dendrite membrane, where contact with neighboring axons is formed in order to receive synaptic input. Changes in size, shape, and density of synaptic...
12.
Popugaeva E, Pchitskaya E, Bezprozvanny I
Antioxid Redox Signal
. 2018 Jun;
29(12):1176-1188.
PMID: 29890840
Significance: Calcium (Ca) hypothesis of Alzheimer's disease (AD) gains popularity. It points to new signaling pathways that may underlie AD pathogenesis. Based on calcium hypothesis, novel targets for the development...
13.
Pchitskaya E, Kraskovskaya N, Chernyuk D, Popugaeva E, Zhang H, Vlasova O, et al.
Sci Rep
. 2017 Dec;
7(1):17625.
PMID: 29247211
Mushroom spines form strong synaptic contacts and are essential for memory storage. We have previously demonstrated that neuronal store-operated calcium entry (nSOC) in hippocampal neurons is regulated by STIM2 protein....
14.
Pchitskaya E, Popugaeva E, Bezprozvanny I
Cell Calcium
. 2017 Jul;
70:87-94.
PMID: 28728834
Calcium (Ca) is a ubiquitous second messenger that regulates various activities in eukaryotic cells. Especially important role calcium plays in excitable cells. Neurons require extremely precise spatial-temporal control of calcium-dependent...
15.
Zhang H, Sun S, Wu L, Pchitskaya E, Zakharova O, Fon Tacer K, et al.
J Neurosci
. 2016 Nov;
36(47):11837-11850.
PMID: 27881772
Significance Statement: Mushroom dendritic spine structures are essential for memory storage and the loss of mushroom spines may explain memory defects in Alzheimer's disease (AD). This study demonstrated that Transient...
16.
Popugaeva E, Pchitskaya E, Bezprozvanny I
Biochem Biophys Res Commun
. 2016 Sep;
483(4):998-1004.
PMID: 27641664
Alzheimer's disease (AD) is the disease of lost memories. Synaptic loss is a major reason for memory defects in AD. Signaling pathways involved in memory loss in AD are under...
17.
Zhang H, Wu L, Pchitskaya E, Zakharova O, Saito T, Saido T, et al.
J Neurosci
. 2015 Oct;
35(39):13275-86.
PMID: 26424877
Alzheimer's disease (AD) is the most common reason for elderly dementia in the world. We proposed that memory loss in AD is related to destabilization of mushroom postsynaptic spines involved...
18.
Popugaeva E, Pchitskaya E, Speshilova A, Alexandrov S, Zhang H, Vlasova O, et al.
Mol Neurodegener
. 2015 Aug;
10:37.
PMID: 26275606
Background: Alzheimer disease (AD) is a disease of lost memories. Mushroom postsynaptic spines play a key role in memory storage, and loss of mushroom spines has been proposed to be...
19.
Zhang H, Liu J, Sun S, Pchitskaya E, Popugaeva E, Bezprozvanny I
J Alzheimers Dis
. 2015 Jan;
45(2):561-80.
PMID: 25589721
Alzheimer's disease (AD) and aging result in impaired ability to store memories, but the cellular mechanisms responsible for these defects are poorly understood. Presenilin 1 (PS1) mutations are responsible for...