Efthymia Chantzi
Overview
Explore the profile of Efthymia Chantzi including associated specialties, affiliations and a list of published articles.
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7
Citations
17
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Recent Articles
1.
Chantzi E, Hammerling U, Gustafsson M
Comput Biol Med
. 2024 Jun;
178:108748.
PMID: 38925084
The CUSP9 protocol is a polypharmaceutical strategy aiming at addressing the complexity of glioblastoma by targeting multiple pathways. Although the rationale for this 9-drug cocktail is well-supported by theoretical and...
2.
Neidlin M, Chantzi E, Macheras G, Gustafsson M, Alexopoulos L
Ann Biomed Eng
. 2020 May;
48(10):2438-2448.
PMID: 32472364
Osteoarthritis (OA) is characterized by irreversible cartilage degradation with very limited therapeutic interventions. Drug candidates targeted at prototypic players had limited success until now and systems based approaches might be...
3.
Chantzi E, Neidlin M, Macheras G, Alexopoulos L, Gustafsson M
PLoS One
. 2020 May;
15(5):e0232989.
PMID: 32407402
Multi drug treatments are increasingly used in the clinic to combat complex and co-occurring diseases. However, most drug combination discovery efforts today are mainly focused on anticancer therapy and rarely...
4.
Neidlin M, Chantzi E, Macheras G, Gustafsson M, Alexopoulos L
PLoS One
. 2019 Oct;
14(10):e0224231.
PMID: 31634377
The pathophysiology of osteoarthritis (OA) involves dysregulation of anabolic and catabolic processes associated with a broad panel of proteins that ultimately lead to cartilage degradation. An increased understanding about these...
5.
Chantzi E, Jarvius M, Niklasson M, Segerman A, Gustafsson M
BMC Bioinformatics
. 2019 Jun;
20(1):304.
PMID: 31164078
Background: Pharmacological treatment of complex diseases using more than two drugs is commonplace in the clinic due to better efficacy, decreased toxicity and reduced risk for developing resistance. However, many...
6.
Chantzi E, Jarvius M, Niklasson M, Segerman A, Gustafsson M
BMC Bioinformatics
. 2018 Nov;
19(1):453.
PMID: 30477419
Background: Large-scale pairwise drug combination analysis has lately gained momentum in drug discovery and development projects, mainly due to the employment of advanced experimental-computational pipelines. This is fortunate as drug...
7.
Eriksson A, Chantzi E, Fryknas M, Gullbo J, Nygren P, Gustafsson M, et al.
Leuk Res
. 2017 Nov;
63:41-46.
PMID: 29100024
We previously reported that the anti-malarial drug quinacrine has potential to be repositioned for treatment of acute myeloid leukemia (AML). As a next step towards clinical use, we assessed the...