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» Authors » Edward Kien Yee Yapp

Edward Kien Yee Yapp

Explore the profile of Edward Kien Yee Yapp including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 224
Followers 0
Related Specialties
Biochemistry
Biology
Biotechnology
Top 10 Co-Authors
Nguyen Quoc Khanh Le
Hui-Yuan Yeh
N Nagasundaram
Yu-Yen Ou
Tuan-Tu Huynh
Cheng-Yu Chen
Matthew Chin Heng Chua
Quang-Thai Ho
Duyen Thi Do
Fang-Ying Chiu
Published In
Anal Biochem
Front Bioeng Biotechnol
BMC Bioinformatics
Comput Struct Biotechnol J
Comput Methods Programs Biomed
Affiliations
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Recent Articles
1.
XGBoost Improves Classification of MGMT Promoter Methylation Status in IDH1 Wildtype Glioblastoma
Le N, Do D, Chiu F, Yapp E, Yeh H, Chen C
J Pers Med . 2020 Sep; 10(3). PMID: 32942564
Approximately 96% of patients with glioblastomas (GBM) have IDH1 wildtype GBMs, characterized by extremely poor prognosis, partly due to resistance to standard temozolomide treatment. O6-Methylguanine-DNA methyltransferase (MGMT) promoter methylation status...
2.
Computational identification of vesicular transport proteins from sequences using deep gated recurrent units architecture
Le N, Yapp E, Nagasundaram N, Chua M, Yeh H
Comput Struct Biotechnol J . 2020 Jan; 17:1245-1254. PMID: 31921391
Protein function prediction is one of the most well-studied topics, attracting attention from countless researchers in the field of computational biology. Implementing deep neural networks that help improve the prediction...
3.
Classifying Promoters by Interpreting the Hidden Information of DNA Sequences via Deep Learning and Combination of Continuous FastText N-Grams
Le N, Yapp E, Nagasundaram N, Yeh H
Front Bioeng Biotechnol . 2019 Nov; 7:305. PMID: 31750297
A promoter is a short region of DNA (100-1,000 bp) where transcription of a gene by RNA polymerase begins. It is typically located directly upstream or at the 5' end...
4.
Identification of clathrin proteins by incorporating hyperparameter optimization in deep learning and PSSM profiles
Le N, Huynh T, Yapp E, Yeh H
Comput Methods Programs Biomed . 2019 Jul; 177:81-88. PMID: 31319963
Background And Objectives: Clathrin is an adaptor protein that serves as the principal element of the vesicle-coating complex and is important for the membrane cleavage to dispense the invaginated vesicle...
5.
ET-GRU: using multi-layer gated recurrent units to identify electron transport proteins
Le N, Yapp E, Yeh H
BMC Bioinformatics . 2019 Jul; 20(1):377. PMID: 31277574
Background: Electron transport chain is a series of protein complexes embedded in the process of cellular respiration, which is an important process to transfer electrons and other macromolecules throughout the...
6.
iMotor-CNN: Identifying molecular functions of cytoskeleton motor proteins using 2D convolutional neural network via Chou's 5-step rule
Le N, Yapp E, Ou Y, Yeh H
Anal Biochem . 2019 Apr; 575:17-26. PMID: 30930199
Motor proteins are the driving force behind muscle contraction and are responsible for the active transportation of most proteins and vesicles in the cytoplasm. There are three superfamilies of cytoskeletal...
7.
iEnhancer-5Step: Identifying enhancers using hidden information of DNA sequences via Chou's 5-step rule and word embedding
Le N, Yapp E, Ho Q, Nagasundaram N, Ou Y, Yeh H
Anal Biochem . 2019 Mar; 571:53-61. PMID: 30822398
An enhancer is a short (50-1500bp) region of DNA that plays an important role in gene expression and the production of RNA and proteins. Genetic variation in enhancers has been...