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Edward E Morrisey

Explore the profile of Edward E Morrisey including associated specialties, affiliations and a list of published articles. Areas
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Articles 192
Citations 13502
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Recent Articles
1.
Zhu X, Xu M, Portal C, Lin Y, Ferdinand A, Peng T, et al.
Nat Commun . 2025 Feb; 16(1):1663. PMID: 39955307
Meibomian glands secrete lipid-rich meibum, which prevents tear evaporation. Aging-related Meibomian gland shrinkage may result in part from stem cell exhaustion and is associated with evaporative dry eye disease, a...
2.
Niethamer T, Planer J, Morley M, Babu A, Zhao G, Basil M, et al.
Cell Stem Cell . 2025 Jan; 32(2):302-321.e6. PMID: 39818203
Functional regeneration of the lung's gas exchange surface following injury requires the coordination of a complex series of cell behaviors within the alveolar niche. Using single-cell transcriptomics combined with lineage...
3.
Jones D, Morley M, Li X, Ying Y, Zhao G, Schaefer S, et al.
Science . 2024 Dec; 386(6727):eado5561. PMID: 39666855
Severe lung injury causes airway basal stem cells to migrate and outcompete alveolar stem cells, resulting in dysplastic repair. We found that this "stem cell collision" generates an injury-induced tissue...
4.
Zhu X, Xu M, Portal C, Lin Y, Ferdinand A, Peng T, et al.
bioRxiv . 2024 Aug; PMID: 39149265
Meibomian glands secrete lipid-rich meibum, which prevents tear evaporation. Aging-related Meibomian gland shrinkage may result in part from stem cell exhaustion and is associated with evaporative dry eye disease, a...
5.
Burgess C, Huang J, Bawa P, Alysandratos K, Minakin K, Ayers L, et al.
Cell Stem Cell . 2024 Apr; 31(5):657-675.e8. PMID: 38642558
Alveolar epithelial type I cells (AT1s) line the gas exchange barrier of the distal lung and have been historically challenging to isolate or maintain in cell culture. Here, we engineer...
6.
Jones D, Morley M, Li X, Ying Y, Cardenas-Diaz F, Li S, et al.
bioRxiv . 2024 Mar; PMID: 38529490
Severe lung injury causes basal stem cells to migrate and outcompete alveolar stem cells resulting in dysplastic repair and a loss of gas exchange function. This "stem cell collision" is...
7.
Basil M, Alysandratos K, Kotton D, Morrisey E
Cell Stem Cell . 2024 Mar; 31(4):439-454. PMID: 38492572
The respiratory system acts as both the primary site of gas exchange and an important sensor and barrier to the external environment. The increase in incidences of respiratory disease over...
8.
Callaway D, Penkala I, Zhou S, Knowlton J, Cardenas-Diaz F, Babu A, et al.
J Clin Invest . 2024 Mar; 134(6). PMID: 38488000
Premature birth disrupts normal lung development and places infants at risk for bronchopulmonary dysplasia (BPD), a disease disrupting lung health throughout the life of an individual and that is increasing...
9.
Cai L, Gao Y, DeBerardinis R, Acquaah-Mensah G, Aidinis V, Beane J, et al.
bioRxiv . 2024 Mar; PMID: 38464291
Lung cancer, the leading cause of cancer mortality, exhibits diverse histological subtypes and genetic complexities. Numerous preclinical mouse models have been developed to study lung cancer, but data from these...
10.
Naik A, Forrest K, Paul O, Issah Y, Valekunja U, Tang S, et al.
JCI Insight . 2024 Mar; 9(5). PMID: 38456509
No abstract available.